A Beginner’s Guide to Cryo-EM for Battery Research

IF 9.6 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Nano Letters Pub Date : 2025-04-22 DOI:10.1021/acs.nanolett.5c00740

Keyue Liang, Xintong Yuan, Xin Chen, Bo Liu, Jung Tae Kim, Jiayi Yu, Dingyi Zhao, Yuzhang Li

引用次数: 0

Abstract

Cryogenic electron microscopy (cryo-EM) has shown great promise in preserving and characterizing beam-sensitive battery materials and interfaces at atomic resolution. With the growing interest in adopting cryo-EM for battery research, this review provides detailed and practical guidance for researchers on cryo-EM workflows including sample preparation and transfer, imaging, data acquisition, and analysis. Strategies for minimizing artifacts during sample preparation and imaging processes are discussed along with approaches to address potential pitfalls in data analysis to ensure accurate interpretation. Finally, this review explores the challenges and opportunities for advancing the cryo-EM technique to further enhance its impact on future developments in battery research.

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Cryo-EM电池研究新手指南

低温电子显微镜（cryo-EM）在原子分辨率下保存和表征光束敏感电池材料和界面方面显示出巨大的前景。随着人们对低温电镜技术在电池研究中的应用越来越感兴趣，本综述为研究人员提供了详细和实用的低温电镜工作流程指导，包括样品制备和转移、成像、数据采集和分析。讨论了在样品制备和成像过程中最小化伪影的策略，以及解决数据分析中潜在缺陷的方法，以确保准确的解释。最后，本文探讨了推进低温电镜技术的挑战和机遇，以进一步增强其对电池研究未来发展的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nano Letters 工程技术-材料科学：综合

CiteScore

16.80

自引率

2.80%

发文量

1182

审稿时长

1.4 months

期刊介绍： Nano Letters serves as a dynamic platform for promptly disseminating original results in fundamental, applied, and emerging research across all facets of nanoscience and nanotechnology. A pivotal criterion for inclusion within Nano Letters is the convergence of at least two different areas or disciplines, ensuring a rich interdisciplinary scope. The journal is dedicated to fostering exploration in diverse areas, including: - Experimental and theoretical findings on physical, chemical, and biological phenomena at the nanoscale - Synthesis, characterization, and processing of organic, inorganic, polymer, and hybrid nanomaterials through physical, chemical, and biological methodologies - Modeling and simulation of synthetic, assembly, and interaction processes - Realization of integrated nanostructures and nano-engineered devices exhibiting advanced performance - Applications of nanoscale materials in living and environmental systems Nano Letters is committed to advancing and showcasing groundbreaking research that intersects various domains, fostering innovation and collaboration in the ever-evolving field of nanoscience and nanotechnology.