Pediatric Case of Crohn Disease, Immunoglobulin A Nephropathy, and Atopic Dermatitis.

IF 6.2 2区医学 Q1 PEDIATRICS

Pediatrics Pub Date : 2025-04-22 DOI:10.1542/peds.2024-068803

Yoshihiko Sugino,Hideki Ban,Yuichiro Yoshino,Yugo Takaki,Akio Furuse

引用次数: 0

Abstract

A few studies have reported immunoglobulin A nephropathy (IgAN) complications in pediatric patients with Crohn disease (CD). Additionally, reports of severe atopic dermatitis (AD) complicating CD with IgAN are rare. In this case report, we review the case of a 10-year-old boy with CD later complicated by IgAN and severe AD at various time points. In his treatment course, he required multiple concurrent therapies, including upadacitinib and infliximab, to achieve remission for all 3 conditions. This case reports successful simultaneous treatment with separate agents in a pediatric case of CD complicated by severe AD.

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克罗恩病、免疫球蛋白A肾病和特应性皮炎的儿童病例。

有少数研究报告了克罗恩病（CD）儿童患者的免疫球蛋白 A 肾病（IgAN）并发症。此外，CD并发严重特应性皮炎（AD）和IgAN的报道也很少见。在本病例报告中，我们回顾了一名 10 岁男孩的病例，他患有 CD，后来在不同时间并发了 IgAN 和严重的 AD。在治疗过程中，他需要同时接受多种治疗，包括达帕替尼（upadacitinib）和英夫利昔单抗（infliximab），才能使这三种疾病都得到缓解。本病例报告了在一例CD并发严重AD的儿科病例中同时使用不同药物治疗的成功案例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatrics 医学-小儿科

CiteScore

12.80

自引率

5.00%

发文量

791

审稿时长

2-3 weeks

期刊介绍： The Pediatrics® journal is the official flagship journal of the American Academy of Pediatrics (AAP). It is widely cited in the field of pediatric medicine and is recognized as the leading journal in the field. The journal publishes original research and evidence-based articles, which provide authoritative information to help readers stay up-to-date with the latest developments in pediatric medicine. The content is peer-reviewed and undergoes rigorous evaluation to ensure its quality and reliability. Pediatrics also serves as a valuable resource for conducting new research studies and supporting education and training activities in the field of pediatrics. It aims to enhance the quality of pediatric outpatient and inpatient care by disseminating valuable knowledge and insights. As of 2023, Pediatrics has an impressive Journal Impact Factor (IF) Score of 8.0. The IF is a measure of a journal's influence and importance in the scientific community, with higher scores indicating a greater impact. This score reflects the significance and reach of the research published in Pediatrics, further establishing its prominence in the field of pediatric medicine.