New Evidence, Creative Insights, and Strategic Solutions: Advancing the Understanding and Practice of Diabetes Osteoporosis

IF 3.7 2区医学 Q2 ENDOCRINOLOGY & METABOLISM

Journal of Diabetes Pub Date : 2025-04-23 DOI:10.1111/1753-0407.70091

Bei Tao, Ximei Shen, Guangfei Li, Xiyu Wu, Yuying Yang, Chunxiang Sheng, Yun Zhang, Ling Wang, Zhiyun Zhao, Qi Song, Dewen Yan, Sunjie Yan, Youjia Xu, Huijuan Yuan, Houde Zhou, Jianmin Liu

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引用次数: 0

Abstract

Background

Diabetes osteoporosis is a debilitating condition that significantly impacts human health. However, it is often underdiagnosed and not addressed in a timely or appropriate manner.

Methods

Recent studies were reviewed to explore the roles of energy metabolism, sarcopeina, low-grade inflammation and gut microbiota in the development of diabetes osteoporosis.

Results

Osteoporosis in diabetic patients differs from primary osteoporosis. Novel biomarkers and risk factors that are biologically, physiologically, and pathologically linked to the development of diabetes osteoporosis are emerging, necessitating a shift in strategies for diagnosis, risk stratification, and prevention of diabetes osteoporosis.

Conclusions

There is an urgent need to approach this disorder from a fresh perspective, initiating a range of basic research and clinical investigations.

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新的证据，创造性的见解和战略解决方案：推进糖尿病骨质疏松症的理解和实践

糖尿病骨质疏松症是一种严重影响人类健康的衰弱性疾病。然而，它往往被诊断不足，没有得到及时或适当的处理。方法综述近年来的研究成果，探讨能量代谢、肌肉、低度炎症和肠道菌群在糖尿病骨质疏松发生中的作用。结果糖尿病骨质疏松症不同于原发性骨质疏松症。新的生物标志物和危险因素与糖尿病骨质疏松症的发展在生物学、生理学和病理学上都有联系，这要求糖尿病骨质疏松症的诊断、风险分层和预防策略发生转变。结论迫切需要从全新的角度来看待这种疾病，开展一系列的基础研究和临床调查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

CiteScore

6.50

自引率

2.20%

发文量

审稿时长

>12 weeks

期刊介绍： Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation. The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.