Mohammed Taib Fatih, Mohammed Abdalla Mahmood, Mohammed Khalid Mahmood, Amanj Ismael Tahir, Handren Ameer Kurda, Mohammed Aso Abdulghafor, Balen Hamid Qadir, Zana Fuad Noori
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引用次数: 0
Abstract
Fibrous dysplasia (FD) is a rare, benign fibro-osseous lesion characterized by replacement of normal bone with extensive fibrous stroma due to abnormalities in osteoblast differentiation. After puberty and during adulthood, FD lesions usually become quiescent. However, some cases show signs of regrowth and reactivation. Here, we report a previously stable maxillary FD case in a 32-year-old man reactivated after a mild COVID-19 infection. We hypothesize that SARS-CoV-2 may utilize diverse mechanisms to induce tumor/cancer in multiple organs, including initiating inflammatory cascades and modifying tumor-suppressing pathways. The capacity of SARS-CoV-2 to enhance the expression of proinflammatory and tumorigenic molecules necessitates further research to ascertain any correlation between this viral infection and FD or other similar diseases.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).