Thyroid cancer

Jordi L. Reverter
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Abstract

In recent decades, the diagnosis of thyroid cancer, especially the papillary type, has increased significantly due to the use of imaging techniques such as ultrasound. For this reason, it is essential to rationalize diagnosis and treatment, since the behavior of thyroid cancer varies from slow-progressing tumors to highly aggressive ones. The application of risk assessment systems for ultrasound images and the optimization of cytology incorporating molecular studies allows cases to be stratified in order to select therapy on an individual basis. Currently, attempts are being made to avoid overtreatment in low-risk tumors, with active surveillance or minimally invasive techniques. The administration of radioiodine is indicated according to risk, with lower doses, and in advanced cases, oncospecific systemic treatments are being incorporated. The management of thyroid cancer requires a multidisciplinary team and population studies and quality clinical trials are necessary to update treatment guidelines.
甲状腺癌
近几十年来,由于超声等成像技术的使用,甲状腺癌的诊断,特别是乳头状型甲状腺癌的诊断显著增加。因此,合理的诊断和治疗是至关重要的,因为甲状腺癌的行为从缓慢进展的肿瘤到高度侵袭性的肿瘤各不相同。超声图像风险评估系统的应用和细胞学优化结合分子研究允许病例分层,以便在个体基础上选择治疗。目前,正在尝试通过主动监测或微创技术来避免低风险肿瘤的过度治疗。放射性碘的施用是根据危险情况确定的,剂量较低,在晚期病例中,正在纳入针对肿瘤的全身治疗。甲状腺癌的管理需要一个多学科的团队,人口研究和高质量的临床试验是必要的,以更新治疗指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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