Cardiovascular death in patients with acute heart failure in sinus rhythm: Results from the RICA registry

Medicina clinica (English ed.) Pub Date : 2025-03-20 DOI:10.1016/j.medcle.2024.10.026

Alberto Elpidio Calvo-Elías , Manuel Méndez-Bailón , Francisco Javier Martín-Sánchez , Rubén Ángel Martín-Sánchez , Elpidio Calvo-Manuel , Prado Salamanca-Bautista , José Pérez-Silvestre , Manuel Montero-Pérez-Baquero , on behalf of the RICA registry researchers

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Abstract

Introduction

Patients with heart failure in sinus rhythm may be at significant risk of major cardiovascular events, including cardiovascular death (CV death).

Objective

To assess CV mortality at a one-year follow up of those patients with heart failure and sinus rhythm, according to LVEF subgroups.

Methods

A prospective and multicentric study was conducted with patients in sinus rhythm included in the National Registry of Heart Failure. Firstly, a demographic, clinical and treatment analysis has been made comparing CV death. Secondly, a multivariate analysis of logistic regression was made including those CV death factors. Lastly, a Kaplan Meyer one year survival was made including LVEF.

Results

Of all 2040 patients included 14.8% presented CV death. The mortality predictors were Barthel index (OR 0.987 (0.982−0.992) [p < 0.001]), LVEF < 40% (OR 1.514 (1.144−2.003) [p 0.003]) and Charlson index (OR 1,069 (1.016−1.124) [p 0.01]).

Conclusion

According to our results CV death has been shown to be higher in those patients with reduced LVEF in sinus rhythm and worst score in Barthel index and Charlson scale.

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窦性心律急性心力衰竭患者的心血管死亡：来自RICA登记的结果

窦性心律心力衰竭患者可能有重大心血管事件的显著风险，包括心血管死亡（CV死亡）。目的根据LVEF亚组评估心力衰竭和窦性心律患者随访一年的CV死亡率。方法采用一项前瞻性多中心研究，纳入国家心力衰竭登记处的窦性心律患者。首先，对CV死亡进行了人口学、临床和治疗分析。其次，对CV死亡因素进行多因素logistic回归分析。最后，Kaplan Meyer一年生存率包括LVEF。结果在所有2040例患者中，14.8%出现CV死亡。死亡率预测因子为Barthel指数(OR 0.987 (0.982 ~ 0.992)；0.001]), LVEF <；40% （OR 1.514(1.144−2.003)[p 0.003]）和Charlson指数（OR 1,069(1.016−1.124)[p 0.01]）。结论窦性心律LVEF降低、Barthel指数和Charlson评分最差的患者心血管死亡率较高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina clinica (English ed.)

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