Promising impacts of Achillea spp., beyond A medicinal plant, against toxins, toxicities, and injuries: In vivo and in vitro mechanisms

IF 2.3 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochemistry and Biophysics Reports Pub Date : 2025-04-22 DOI:10.1016/j.bbrep.2025.102023

Mohammad Mahdi Dabbaghi , Mohammad Saleh Fadaei , Maral Goldoozian , Mohammad Reza Fadaei , Vafa Baradaran Rahimi , Vahid Reza Askari

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引用次数: 0

Abstract

Natural toxins produced by various living organisms pose significant risks to health, food security, and environmental balance through inhalation, ingestion, and other exposure routes. This review focuses on the ameliorative effects of different Achillea species, which comprise over 130 perennial herbs known for their therapeutic properties. A systematic examination of data from Scopus, PubMed, and Web of Science was conducted, encompassing various studies without date restrictions, ensuring a comprehensive selection of articles based on full-text availability. The results of this study indicate that Achillea millefolium exhibits anti-hyperglycemic and anti-hyperlipidemic properties, enhances collagen proliferation regulation, suppresses inflammatory responses, and displays significant antioxidant activity. Similarly, A. wilhelmsii has been shown to have hepatoprotective effects, as evidenced by reduced malondialdehyde levels and increased total thiol concentrations. A. fragrantissima has also been demonstrated to have cardioprotective effects, with a decrease in inflammatory markers and edema levels. The protective benefits of other species within the Achillea genus extend to various toxins. This comprehensive review underscores the potential of Achillea species as natural remedies for combating toxicities and promoting health.

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阿喀琉斯属植物在抗毒素、毒性和损伤方面的潜在影响：体内和体外机制

各种生物产生的天然毒素通过吸入、摄入和其他接触途径对健康、粮食安全和环境平衡构成重大风险。这篇综述的重点是不同种类的阿基那植物的改善作用，其中包括130多种多年生草本植物已知的治疗特性。对来自Scopus、PubMed和Web of Science的数据进行了系统的检查，包括了各种没有日期限制的研究，确保了基于全文可用性的文章的全面选择。本研究结果表明，千叶阿喀琉叶具有抗高血糖和抗高脂血症的特性，增强胶原蛋白增殖调节，抑制炎症反应，并具有显著的抗氧化活性。类似地，A. wilhelmsii已被证明具有保护肝脏的作用，如降低丙二醛水平和增加总硫醇浓度所证明的那样。香芹也被证明具有心脏保护作用，可以减少炎症标志物和水肿水平。阿喀琉斯属其他物种的保护作用延伸到各种毒素。本综述强调了阿喀琉叶属植物作为抗毒性和促进健康的天然药物的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biochemistry and Biophysics Reports Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

4.60

自引率

0.00%

发文量

191

审稿时长

59 days

期刊介绍： Open access, online only, peer-reviewed international journal in the Life Sciences, established in 2014 Biochemistry and Biophysics Reports (BB Reports) publishes original research in all aspects of Biochemistry, Biophysics and related areas like Molecular and Cell Biology. BB Reports welcomes solid though more preliminary, descriptive and small scale results if they have the potential to stimulate and/or contribute to future research, leading to new insights or hypothesis. Primary criteria for acceptance is that the work is original, scientifically and technically sound and provides valuable knowledge to life sciences research. We strongly believe all results deserve to be published and documented for the advancement of science. BB Reports specifically appreciates receiving reports on: Negative results, Replication studies, Reanalysis of previous datasets.