The effects of in-hospital orthogeriatric care on health-related quality of life: a systematic review and meta-analysis

Abstract

Background Orthogeriatric care has been shown to effectively reduce mortality and morbidity and has a potential impact on health-related quality of life (HRQoL). This systematic review and meta-analysis summarises the effects of orthogeriatric care on HRQoL in hip fracture patients. Methods The review protocol was registered in International Prospective Register of Systematic Reviews (PROSPERO): CRD42021206280. We searched Medline and EMBASE from inception to January 2024 without language restrictions. We included randomised and non-randomised controlled trials comparing HRQoL in older hip fracture patients receiving orthogeriatric care to other fracture care. Study quality was evaluated using the Revised Cochrane Risk-of-Bias (RoB) tool or the Newcastle–Ottawa Scale (NOS). Pooled standardised mean differences (SMDs) were calculated using random-effects models. We reported according to the Preferred Reporting Items of Systematic reviews and Meta-Analyses guidelines. Results Eight studies involving 2411 patients were included, all employing various orthogeriatric care models with moderate to good methodological quality, based on the RoB tool and NOS. However, substantial clinical heterogeneity was present due to variations in study design, number and execution of intervention components, outcome measures and patient populations. Despite this variability, meta-analysis showed that in-hospital orthogeriatric care, compared to usual care, led to a small but statistically significant improvement in overall HRQoL (SMD 0.18, 95% CI 0.06–0.30) with moderate heterogeneity (I2 = 47%). Conclusion In-hospital orthogeriatric care has a small but significant effect on HRQoL. This study highlights the need for clear descriptions of orthogeriatric care models, their implementation, fidelity and contextual factors. High-quality future research is essential to advance clinical practice, refine care models, address methodological limitations and prioritise patient-centred short- and long-term HRQoL outcomes.