Autochthonous human case of Echinococcus ortleppi cystic echinococcosis in Brittany, Western part of France

IF 2.9 Q2 PARASITOLOGY

Food and Waterborne Parasitology Pub Date : 2025-04-17 DOI:10.1016/j.fawpar.2025.e00264

Brice Autier , Marion Baldeyrou , Heithem Jeddou , Coralie Barrera , Jean-Pierre Gangneux

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Abstract

Human cystic echinococcosis (CE) is a worldwide infection due to the larval stage of Echinococcus granulosus sensu lato, a taeniid tapeworm of canids. Identification of the causative agent at species level relies on molecular methods such as DNA sequencing or species-specific qPCR, which are rarely used for routine case management. Among the different species within the E. granulosus complex, Echinococcus ortleppi (E. granulosus genotype G5 former “cattle strain”) has been reported in only 19 human cases worldwide, including 3 in France. We report the 20th case of E. ortleppi cystic echinococcosis, which is an French autochthonous case of a patient without usual risk factors for CE, and living in an area not known to be endemic for E. ortleppi. This case highlights that medical community should be aware of the benefits from molecular epidemiology in understanding the landscape of parasitic diseases.

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法国西部布列塔尼本地人类奥特皮棘球蚴囊性棘球蚴病一例

人类囊性棘球蚴病（CE）是一种由犬科动物的绦虫——细粒棘球绦虫幼虫引起的世界性传染病。在物种水平上鉴定病原体依赖于分子方法，如DNA测序或物种特异性qPCR，这些方法很少用于常规病例管理。在颗粒棘球绦虫复合体的不同种类中，全球仅在19例人类病例中报告了棘球绦虫（颗粒棘球绦虫基因型G5以前的“牛株”），其中包括法国的3例。我们报告第20例奥特皮囊性棘球蚴病，这是一个法国本土病例，患者没有常见的CE危险因素，生活在一个未知的奥特皮棘球蚴流行地区。这个病例强调了医学界应该意识到分子流行病学在了解寄生虫病的情况方面的好处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food and Waterborne Parasitology Immunology and Microbiology-Parasitology

CiteScore

5.10

自引率

4.00%

发文量

审稿时长

13 weeks

期刊介绍： Food and Waterborne Parasitology publishes high quality papers containing original research findings, investigative reports, and scientific proceedings on parasites which are transmitted to humans via the consumption of food or water. The relevant parasites include protozoa, nematodes, cestodes and trematodes which are transmitted by food or water and capable of infecting humans. Pertinent food includes products of animal or plant origin which are domestic or wild, and consumed by humans. Animals and plants from both terrestrial and aquatic sources are included, as well as studies related to potable and other types of water which serve to harbor, perpetuate or disseminate food and waterborne parasites. Studies dealing with prevalence, transmission, epidemiology, risk assessment and mitigation, including control measures and test methodologies for parasites in food and water are of particular interest. Evidence of the emergence of such parasites and interactions among domestic animals, wildlife and humans are of interest. The impact of parasites on the health and welfare of humans is viewed as very important and within scope of the journal. Manuscripts with scientifically generated information on associations between food and waterborne parasitic diseases and lifestyle, culture and economies are also welcome. Studies involving animal experiments must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences.