Jawad Shafqat , Zainab Shehzadi , Muhammad Usama bin Shabbir , Maira Ramzan , Muhammad Umer Javaid , Sundas Ali
{"title":"Unraveling the mysterious link: Thromboembolic events following COVID-19 vaccination – A comprehensive case report","authors":"Jawad Shafqat , Zainab Shehzadi , Muhammad Usama bin Shabbir , Maira Ramzan , Muhammad Umer Javaid , Sundas Ali","doi":"10.1016/j.hmedic.2025.100198","DOIUrl":null,"url":null,"abstract":"<div><div>This case report delves into the intriguing phenomenon of post-vaccination thrombosis, shedding light on the unexpected thromboembolic events that have surfaced following the administration of COVID-19 vaccines. With the rise in reports of venous thromboembolism, particularly following the AstraZeneca and mRNA vaccines, Herein, we report a case of RPF following Vaxzevria-AstraZeneca COVID-19 mRNA vaccination. A 34-year-old male patient with no history of autoimmune diseases presented with acute onset of epigastric pain two weeks post-vaccination.Laboratory findings reveal thrombocytopenia and elevated D-dimers. Imaging through abdominal CT and CT venography confirmed extensive thrombosis in the IVC, iliac veins, renal veins, and hepatic vein. This report underscores the need for heightened awareness of potential venous thromboembolism, particularly IVC thrombosis, in patients presenting with abdominal pain following COVID-19 vaccination.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100198"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918625000439","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This case report delves into the intriguing phenomenon of post-vaccination thrombosis, shedding light on the unexpected thromboembolic events that have surfaced following the administration of COVID-19 vaccines. With the rise in reports of venous thromboembolism, particularly following the AstraZeneca and mRNA vaccines, Herein, we report a case of RPF following Vaxzevria-AstraZeneca COVID-19 mRNA vaccination. A 34-year-old male patient with no history of autoimmune diseases presented with acute onset of epigastric pain two weeks post-vaccination.Laboratory findings reveal thrombocytopenia and elevated D-dimers. Imaging through abdominal CT and CT venography confirmed extensive thrombosis in the IVC, iliac veins, renal veins, and hepatic vein. This report underscores the need for heightened awareness of potential venous thromboembolism, particularly IVC thrombosis, in patients presenting with abdominal pain following COVID-19 vaccination.
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