New Dermoscopy Pattern in Nevus-Associated Melanomas

IF 3.9 3区 医学 Q2 CELL BIOLOGY
Nelson Lobos-Guede, Dan Hartmann, Valentina Darlic, Cristina Carrera, Llucia Alos, Susana Puig
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引用次数: 0

Abstract

Melanomas can appear de novo or in association with a pre-existing nevus. The association of melanomas with pre-existing nevi and its role as a melanoma precursor is a controversial issue. Dermoscopy can increase melanoma's diagnostic accuracy and help us suspect nevus-associated melanomas (NAM). Differentiating NAMs clinically and dermoscopically can be challenging. There are few published studies so far describing dermoscopic features of NAM that have differentiated from de novo melanomas, such as multi-component pattern, multifocal pigmentation, atypical pigment network, regression structures, negative pigment network, irregular globules, and streaks. Here, we report four acquired compound NAMs showing a starburst pattern (SP) within the lesion. No publications have reported NAMs with melanoma components in the form of SP arising within the center of the lesion. Therefore, when faced with a compound or intradermal nevus with incipient central reticulated pigmentation, especially if there is no history of trauma or previous surgery, we must pay alert to the possibility of an early development of melanoma.

Abstract Image

痣相关黑色素瘤的新皮肤镜检查模式
黑色素瘤可以是新发的,也可以与已有的痣有关。黑素瘤与已有痣的关系及其作为黑素瘤前体的作用是一个有争议的问题。皮肤镜检查可以提高黑色素瘤的诊断准确性,帮助我们怀疑痣相关性黑色素瘤(NAM)。临床和皮肤镜下鉴别NAMs具有挑战性。目前发表的研究很少描述NAM与新生黑色素瘤不同的皮肤镜特征,如多组分模式、多灶性色素沉着、非典型色素网络、退行性结构、负性色素网络、不规则小球和条纹。在这里,我们报告了四个获得的化合物NAMs在病变内显示星爆模式(SP)。没有出版物报道在病变中心以SP形式出现黑色素瘤成分的NAMs。因此,当面对具有早期中枢网状色素沉着的复合痣或皮内痣时,特别是如果没有创伤史或以前的手术,我们必须警惕早期发展为黑色素瘤的可能性。
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来源期刊
Pigment Cell & Melanoma Research
Pigment Cell & Melanoma Research 医学-皮肤病学
CiteScore
8.90
自引率
2.30%
发文量
54
审稿时长
6-12 weeks
期刊介绍: Pigment Cell & Melanoma Researchpublishes manuscripts on all aspects of pigment cells including development, cell and molecular biology, genetics, diseases of pigment cells including melanoma. Papers that provide insights into the causes and progression of melanoma including the process of metastasis and invasion, proliferation, senescence, apoptosis or gene regulation are especially welcome, as are papers that use the melanocyte system to answer questions of general biological relevance. Papers that are purely descriptive or make only minor advances to our knowledge of pigment cells or melanoma in particular are not suitable for this journal. Keywords Pigment Cell & Melanoma Research, cell biology, melatonin, biochemistry, chemistry, comparative biology, dermatology, developmental biology, genetics, hormones, intracellular signalling, melanoma, molecular biology, ocular and extracutaneous melanin, pharmacology, photobiology, physics, pigmentary disorders
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