{"title":"Helmholtz Health task force to strengthen prevention research and its translation globally","authors":"","doi":"10.1038/s41591-025-03590-1","DOIUrl":null,"url":null,"abstract":"<p>Prevention research aims to understand, mitigate and ultimately avert the onset and progression of disease and the spillover of pathogens. Such research includes the analysis of risk factors and fundamental mechanisms of disease emergence, early detection and screening, stratification into risk groups, and the development and evaluation of preventive interventions. In the face of population aging and escalating planetary health challenges, such as the climate crisis<sup>1</sup>, prevention research is crucial in mitigating the burden of both non-communicable and communicable diseases.</p><p>In recognition of the importance of shifting from reactive medicine to preventative approaches, Helmholtz Health has put together a strategic task force dedicated to prevention research. The Helmholtz Association is the largest scientific organization in Germany and, with an annual budget of €5 billion, one of the leading intramural research programs in Europe. Its mission is to contribute to solving grand challenges faced by society, science and industry, by conducting research in six fields: aeronautics, space and transport; earth and environment; energy; health; matter; and information. Helmholtz Health represents six health research centers across Germany, with a workforce base of approximately 10,000 people, and the German National Cohort (NAKO)<sup>2</sup>. The Helmholtz Health Prevention Task Force comprises interdisciplinary experts from all six research centers and NAKO, covering a wide spectrum of health research areas that include infectious disease, cancer, and cardiovascular, metabolic, respiratory and neurodegenerative diseases. The task force has been tasked with outlining a strategic roadmap for strengthening prevention research and its translation globally.</p>","PeriodicalId":19037,"journal":{"name":"Nature Medicine","volume":"27 1","pages":""},"PeriodicalIF":58.7000,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41591-025-03590-1","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Prevention research aims to understand, mitigate and ultimately avert the onset and progression of disease and the spillover of pathogens. Such research includes the analysis of risk factors and fundamental mechanisms of disease emergence, early detection and screening, stratification into risk groups, and the development and evaluation of preventive interventions. In the face of population aging and escalating planetary health challenges, such as the climate crisis1, prevention research is crucial in mitigating the burden of both non-communicable and communicable diseases.
In recognition of the importance of shifting from reactive medicine to preventative approaches, Helmholtz Health has put together a strategic task force dedicated to prevention research. The Helmholtz Association is the largest scientific organization in Germany and, with an annual budget of €5 billion, one of the leading intramural research programs in Europe. Its mission is to contribute to solving grand challenges faced by society, science and industry, by conducting research in six fields: aeronautics, space and transport; earth and environment; energy; health; matter; and information. Helmholtz Health represents six health research centers across Germany, with a workforce base of approximately 10,000 people, and the German National Cohort (NAKO)2. The Helmholtz Health Prevention Task Force comprises interdisciplinary experts from all six research centers and NAKO, covering a wide spectrum of health research areas that include infectious disease, cancer, and cardiovascular, metabolic, respiratory and neurodegenerative diseases. The task force has been tasked with outlining a strategic roadmap for strengthening prevention research and its translation globally.
期刊介绍:
Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors.
Nature Medicine consider all types of clinical research, including:
-Case-reports and small case series
-Clinical trials, whether phase 1, 2, 3 or 4
-Observational studies
-Meta-analyses
-Biomarker studies
-Public and global health studies
Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.