Annatto concentrate reduces oxidative stress in ewes during metabolic challenge stages

IF 2.5 2区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Animal Feed Science and Technology Pub Date : 2025-04-15 DOI:10.1016/j.anifeedsci.2025.116353

Leticia Jalloul Guimarães , Isabella Guartieri da Silva , Gabriella Capitane Sena , Gabriel Lourenço , Isabella Pereira Azoia , Sandra Maria Simonelli , Fabiola Cristine De Almeida Rego , Débora Cristina Damasceno , Marilice Zundt

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Abstract

This study evaluated the effects of annatto concentrate (ANC) supplementation on oxidative stress markers in ewes during critical reproductive phases: prepartum, postpartum, and weaning. Thirty Dorper crossbred ewes were divided into three groups (n = 10): Control (0 % ANC), 0.5 % ANC, and 1 % ANC. Blood samples were collected at three stages: last third of gestation (100 days), postpartum, and weaning, and analyzed for TAC, MDA, reduced thiols (-SH), hydrogen peroxide (H₂O₂), and the enzymatic activities of catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx). Results indicated that the 1 % ANC dose significantly reduced H₂O₂ and MDA levels during prepartum period (P < 0.05), while the 0.5 % dose enhanced catalase activity during postpartum (P < 0.01). At weaning, the 0.5 % ANC dose also improved oxidative status by increasing SOD and GPx activity (P < 0.05). These findings suggest that ANC supplementation improves oxidative balance in ewes during metabolically demanding periods, offering a natural strategy to enhance animal health and welfare.

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红木浓缩物可降低母羊在代谢挑战阶段的氧化应激

本研究评估了在母羊的关键生殖阶段（准备、产后和断奶）补充红木浓缩物（ANC）对氧化应激标志物的影响。30只杜泊杂交母羊分为3组（n = 10）：对照组（0 % ANC）、0.5 % ANC和1 % ANC。在妊娠最后三分之一（100天）、产后和断奶三个阶段采集血样，分析TAC、MDA、还原性硫醇（-SH）、过氧化氢（H₂O₂）以及过氧化氢酶、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GPx）的酶活性。结果表明，1 % ANC剂量显著降低了产前H₂O₂和MDA水平（P <； 0.05），0.5 %剂量显著提高了产后过氧化氢酶活性（P <； 0.01）。断奶时，0.5 % ANC也通过提高SOD和GPx活性改善了氧化状态（P <； 0.05）。这些发现表明，在代谢要求较高的时期，补充ANC可以改善母羊的氧化平衡，为提高动物健康和福利提供了一种天然策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Animal Feed Science and Technology 农林科学-奶制品与动物科学

CiteScore

6.00

自引率

6.20%

发文量

266

审稿时长

3 months

期刊介绍： Animal Feed Science and Technology is a unique journal publishing scientific papers of international interest focusing on animal feeds and their feeding. Papers describing research on feed for ruminants and non-ruminants, including poultry, horses, companion animals and aquatic animals, are welcome. The journal covers the following areas: Nutritive value of feeds (e.g., assessment, improvement) Methods of conserving and processing feeds that affect their nutritional value Agronomic and climatic factors influencing the nutritive value of feeds Utilization of feeds and the improvement of such Metabolic, production, reproduction and health responses, as well as potential environmental impacts, of diet inputs and feed technologies (e.g., feeds, feed additives, feed components, mycotoxins) Mathematical models relating directly to animal-feed interactions Analytical and experimental methods for feed evaluation Environmental impacts of feed technologies in animal production.