Sonia Fathi-karkan , Sina Nasiri , Maliheh Hasannia , Abbas Rahdar , Mohammad Nouri , Mehrdad Najafi , Arezoo Basiri , Fatemeh Soltani Tehrani , Seyed Mehdi Hashemi , Luiz Fernando Romanholo Ferreira
{"title":"Green carbon dots and theranostic applications","authors":"Sonia Fathi-karkan , Sina Nasiri , Maliheh Hasannia , Abbas Rahdar , Mohammad Nouri , Mehrdad Najafi , Arezoo Basiri , Fatemeh Soltani Tehrani , Seyed Mehdi Hashemi , Luiz Fernando Romanholo Ferreira","doi":"10.1016/j.jddst.2025.106861","DOIUrl":null,"url":null,"abstract":"<div><div>Green carbon dots (GCDs) have emerged as a potential category of nanomaterials owing to their distinctive attributes, which include biocompatibility, low toxicity, increased photoluminescence (PL), and environmental sustainability. This paper thoroughly examines the synthesis of GCDs from renewable carbon sources, their unique features, and their extensive uses in theranostics, including bioimaging, drug administration, photothermal treatment, and molecular diagnostics. The synthesis methods, including hydrothermal, microwave-assisted, and laser ablation procedures, are examined comprehensively, emphasizing their benefits and drawbacks. The study highlights the significance of surface functionalization and heteroatom doping in improving the optical and electrical characteristics of GCDs. Additionally, the capabilities of GCDs in sustainable nanotechnology and their contribution to resolving environmental and medicinal issues are analyzed. This article seeks to elucidate GCDs, including their synthesis, characteristics, and uses, while also delineating prospective research avenues to address current limits and enhance their potential in biological and environmental domains.</div></div>","PeriodicalId":15600,"journal":{"name":"Journal of Drug Delivery Science and Technology","volume":"108 ","pages":"Article 106861"},"PeriodicalIF":4.5000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Drug Delivery Science and Technology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1773224725002643","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Green carbon dots (GCDs) have emerged as a potential category of nanomaterials owing to their distinctive attributes, which include biocompatibility, low toxicity, increased photoluminescence (PL), and environmental sustainability. This paper thoroughly examines the synthesis of GCDs from renewable carbon sources, their unique features, and their extensive uses in theranostics, including bioimaging, drug administration, photothermal treatment, and molecular diagnostics. The synthesis methods, including hydrothermal, microwave-assisted, and laser ablation procedures, are examined comprehensively, emphasizing their benefits and drawbacks. The study highlights the significance of surface functionalization and heteroatom doping in improving the optical and electrical characteristics of GCDs. Additionally, the capabilities of GCDs in sustainable nanotechnology and their contribution to resolving environmental and medicinal issues are analyzed. This article seeks to elucidate GCDs, including their synthesis, characteristics, and uses, while also delineating prospective research avenues to address current limits and enhance their potential in biological and environmental domains.
期刊介绍:
The Journal of Drug Delivery Science and Technology is an international journal devoted to drug delivery and pharmaceutical technology. The journal covers all innovative aspects of all pharmaceutical dosage forms and the most advanced research on controlled release, bioavailability and drug absorption, nanomedicines, gene delivery, tissue engineering, etc. Hot topics, related to manufacturing processes and quality control, are also welcomed.