Physiotherapy in improving the interincisal mouth opening in oral submucous fibrosis: Meta-analysis

Q1 Medicine

Journal of oral biology and craniofacial research Pub Date : 2025-04-18 DOI:10.1016/j.jobcr.2025.04.007

Ashish Bodhade , Alka Dive , Monal Yuwanati , Amol Gadbail , Dhara Dwivedi

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引用次数: 0

Abstract

Background

Oral submucous fibrosis (OSMF) is a chronic, irreversible collagen metabolic disorder resulting in progressive reduction of mouth opening due to submucosal fibrosis. Currently, the benefit of interincisal mouth opening (IMO) has been attributed to physical therapy. This meta-analysis aimed to find evidence about effectiveness of physiotherapy in increasing of IMO.

Method

Literature search was conducted in Scopus, Web of Science, and PubMed databases using "Oral submucous fibrosis", "OSMF", "OSF”, “treatment”, “treatment modalities", "physiotherapy devices", “mouth opening exercise device”, “mouth opening”, “mouth opening device”, and "physiotherapy" search terms to find the relevant studies published till March 2024. Studies evaluating the effectiveness of physiotherapy alone or in combination in improvement of IMO pre-post intervention in OSMF patients were included. Random-effect analysis was carried out to obtain the pooled IMO. Heterogeneity and publication bias was assessed using the I² and funnel plot. The main outcome variable was increase in IMO which was measured on linear scale.

Results

20 studies included in meta-analysis. Physiotherapy alone was found to be effective in improving IMO (4 studies; MD 1.19 [0.18, 2.20]). Further, addition of physiotherapy along with ultrasound (US) (3 studies; MD 3.96 [1.50, 6.42]), medicinal therapy including herbal (13 studies; MD 8.35 [5.18, 11.51]) and surgery (8 studies; MD 21.84 [18.29, 25.38]) improves the IMO.

Conclusion

There is evidence of effectiveness of physiotherapy in improving the IMO. However, evidence need to be substantiated with stringent methodology which is lacking in most of studies.

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物理治疗改善口腔黏膜下纤维化患者的内脏开口：荟萃分析

背景口腔黏膜下纤维化（OSMF）是一种慢性、不可逆的胶原代谢性疾病，由于黏膜下纤维化，导致张口度逐渐减小。目前，颚间张口（IMO）的益处主要归功于物理疗法。方法在 Scopus、Web of Science 和 PubMed 数据库中使用 "Oral submucous fibrosis"、"OSMF"、"OSF"、"treatment"、"treatment modalities"、"physicalotherapy devices"、"mouth opening exercise device"、"mouth opening"、"mouth opening device "和 "physicalotherapy "等检索词进行文献检索，查找截至 2024 年 3 月发表的相关研究。纳入的研究评估了物理治疗单独或联合使用对 OSMF 患者进行干预前 IMO 改善的有效性。采用随机效应分析法得出汇总的 IMO。使用 I2 和漏斗图评估异质性和发表偏倚。主要结果变量为IMO的增加，以线性量表进行测量。结果发现，单独使用物理治疗可有效改善 IMO（4 项研究；MD 1.19 [0.18, 2.20]）。此外，物理治疗与超声波（US）（3 项研究；MD 3.96 [1.50, 6.42]）、药物治疗（包括草药）（13 项研究；MD 8.35 [5.18, 11.51]）和手术（8 项研究；MD 21.84 [18.29, 25.38]）一起使用可改善 IMO。结论有证据表明物理治疗对改善 IMO 有效，但证据需要严格的方法证实，而大多数研究都缺乏这一点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of oral biology and craniofacial research Medicine-Otorhinolaryngology

CiteScore

4.90

自引率

0.00%

发文量

133

审稿时长

167 days

期刊介绍： Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.