Cultural variables influence performance on the MATRICS Consensus Cognitive Battery among people at clinical high risk for psychosis

IF 3.6 2区医学 Q1 PSYCHIATRY

Schizophrenia Research Pub Date : 2025-04-17 DOI:10.1016/j.schres.2025.04.019

Ryan M. Guest , Katrina Aberizk , Jean Addington , Carrie E. Bearden , Kristin S. Cadenhead , Tyrone D. Cannon , Barbara A. Cornblatt , Matcheri S. Keshavan , Daniel H. Mathalon , Diana O. Perkins , William S. Stone , Scott W. Woods , Elaine F. Walker

{"title":"Cultural variables influence performance on the MATRICS Consensus Cognitive Battery among people at clinical high risk for psychosis","authors":"Ryan M. Guest , Katrina Aberizk , Jean Addington , Carrie E. Bearden , Kristin S. Cadenhead , Tyrone D. Cannon , Barbara A. Cornblatt , Matcheri S. Keshavan , Daniel H. Mathalon , Diana O. Perkins , William S. Stone , Scott W. Woods , Elaine F. Walker","doi":"10.1016/j.schres.2025.04.019","DOIUrl":null,"url":null,"abstract":"<div><h3>Background & hypothesis</h3><div>Prior studies suggest that cognitive batteries normed in the U.S. may not be suitable for populations that differ in English proficiency and/or cultural background. Here, we investigated how cultural variables (i.e., length of residence, native English speaker) influence cognitive performance within a U.S. and Canadian sample of people at clinical high risk for psychosis (CHR-P) and healthy control (HC) participants.</div></div><div><h3>Study design</h3><div>The sample consisted of 925 adolescents and adults (664 CHR-P, 261 HC) from the second cohort of the North American Prodromal Longitudinal Study, including 73 (7.9 %) foreign-born participants and 94 (10.2 %) who reported a language other than English as their first language. Multigroup structural equation modeling was used to estimate effects of cultural variables on MATRICS Consensus Cognitive Battery (MCCB) subtests, separately in each diagnostic group.</div></div><div><h3>Study results</h3><div>A structural model that generated unique estimates for all parameters in group models was selected. For CHR-P, longer length of residence in U.S./Canada related to better performance on Animal Naming (β = 0.09, <em>p</em> = .01), whereas being a native English speaker related to better performance on Letter-Number Span (β = 0.14, <em>p =</em> .001) and Hopkins Verbal Learning Test – Revised (β = 0.10, <em>p =</em> .03). In contrast, no such relationships were observed among HCs.</div></div><div><h3>Conclusions</h3><div>Findings extend our understanding of how cultural variables may influence presentation of psychosis-risk syndromes and suggest that being a non-native English speaker or having recently immigrated may hinder performance on certain verbal neuropsychological measures.</div></div>","PeriodicalId":21417,"journal":{"name":"Schizophrenia Research","volume":"280 ","pages":"Pages 60-68"},"PeriodicalIF":3.6000,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Schizophrenia Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0920996425001410","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Background & hypothesis

Prior studies suggest that cognitive batteries normed in the U.S. may not be suitable for populations that differ in English proficiency and/or cultural background. Here, we investigated how cultural variables (i.e., length of residence, native English speaker) influence cognitive performance within a U.S. and Canadian sample of people at clinical high risk for psychosis (CHR-P) and healthy control (HC) participants.

Study design

The sample consisted of 925 adolescents and adults (664 CHR-P, 261 HC) from the second cohort of the North American Prodromal Longitudinal Study, including 73 (7.9 %) foreign-born participants and 94 (10.2 %) who reported a language other than English as their first language. Multigroup structural equation modeling was used to estimate effects of cultural variables on MATRICS Consensus Cognitive Battery (MCCB) subtests, separately in each diagnostic group.

Study results

A structural model that generated unique estimates for all parameters in group models was selected. For CHR-P, longer length of residence in U.S./Canada related to better performance on Animal Naming (β = 0.09, p = .01), whereas being a native English speaker related to better performance on Letter-Number Span (β = 0.14, p = .001) and Hopkins Verbal Learning Test – Revised (β = 0.10, p = .03). In contrast, no such relationships were observed among HCs.

Conclusions

Findings extend our understanding of how cultural variables may influence presentation of psychosis-risk syndromes and suggest that being a non-native English speaker or having recently immigrated may hinder performance on certain verbal neuropsychological measures.

查看原文本刊更多论文

文化变量影响临床精神病高危人群在matrix共识认知电池中的表现

背景,先前的研究表明，美国规范的认知电池可能不适用于英语水平和/或文化背景不同的人群。在这里，我们调查了文化变量（即居住时间长短，母语为英语的人）如何影响美国和加拿大临床精神病高危人群（chrp）和健康对照（HC）参与者的认知表现。样本包括来自北美前驱期纵向研究第二队列的925名青少年和成人（664名chrp， 261名HC），包括73名（7.9%）外国出生的参与者和94名（10.2%）以非英语为第一语言的参与者。使用多组结构方程模型来估计文化变量对每个诊断组的matrix共识认知电池（MCCB）子测试的影响。研究结果选择了对群模型中所有参数产生唯一估计的结构模型。对于chrp，在美国/加拿大居住的时间越长，在动物命名方面的表现越好（β = 0.09, p = 0.01），而母语为英语的人在字母-数字广度（β = 0.14, p = 0.001）和霍普金斯语言学习测试-修订（β = 0.10, p = 0.03）方面的表现越好。相反，在hcc中没有观察到这种关系。结论：研究结果扩展了我们对文化变量如何影响精神病风险综合征表现的理解，并表明非英语母语者或最近移民可能会阻碍某些言语神经心理学测量的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Schizophrenia Research 医学-精神病学

CiteScore

7.50

自引率

8.90%

发文量

429

审稿时长

10.2 weeks

期刊介绍： As official journal of the Schizophrenia International Research Society (SIRS) Schizophrenia Research is THE journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community. More than 6000 institutes have online or print (or both) access to this journal - the largest specialist journal in the field, with the largest readership! Schizophrenia Research''s time to first decision is as fast as 6 weeks and its publishing speed is as fast as 4 weeks until online publication (corrected proof/Article in Press) after acceptance and 14 weeks from acceptance until publication in a printed issue. The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia.