Effects of Transcatheter Arterial Embolization for Chronic Intractable Shoulder Pain: A Prospective Clinical Study

IF 2.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

International Journal of Clinical Practice Pub Date : 2025-04-16 DOI:10.1155/ijcp/9964536

Kun Yung Kim, Young-Min Han, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park, Yu Hui Won, Gi-Wook Kim

{"title":"Effects of Transcatheter Arterial Embolization for Chronic Intractable Shoulder Pain: A Prospective Clinical Study","authors":"Kun Yung Kim, Young-Min Han, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park, Yu Hui Won, Gi-Wook Kim","doi":"10.1155/ijcp/9964536","DOIUrl":null,"url":null,"abstract":"<div>\n Objectives: Based on the idea that the neovessels and nerves are a possible cause of pain, transcatheter arterial embolization (TAE) has been reported as a novel adjunctive treatment with good outcomes. Purpose of this was to examine the short-term outcomes of TAE including 1-day follow-up results in patients with chronic shoulder pain using patient-reported outcome measures.\n Study Design: Prospective study.\n Methods: TAE was performed with a suspension of imipenem/cilastatin sodium in contrast agent. Subjects were assessed before, 1 day after, and 1 month after the procedure using the visual analogue scale (VAS, 0–10), shoulder pain and disability index (SPADI, 0–100), and Constant–Murley score (CMS, 0–100).\n Results: A total of 10 patients were enrolled. All procedures were technically successful with the radial artery approach. Abnormal neovessels with angiographic blushes were identified in all cases, with a mean of 3.3 abnormal neovessels per patient (range, 2–4) and a total of 41 arteries embolized, averaging 4.1 vessels per patient (range, 3–5). Baseline VAS, SPADI, and CMS were 3.5, 50.0, and 47.4, respectively. The 1-day follow-up (VAS, 2.0; SPADI, 26.3; CMS, 68.1; p ≤ 0.001 compared to baseline) and 1-month follow-up (VAS, 1.7; SPADI, 24.3; CMS, 72.8; p ≤ 0.002 compared to baseline) demonstrated significant improvements. The 1-day and 1-month follow-up results were not significantly different.\n Conclusions: Substantial pain relief and functional scales improvement were observed both immediately and 1 month after TAE in chronic intractable shoulder pain. TAE may be an effective alternative treatment for patients with shoulder pain who do not respond to conservative or surgical treatment.\n Trial Registration: Korean Registry of Clinical Trials: KCT0004720\n </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9964536","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1155/ijcp/9964536","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: Based on the idea that the neovessels and nerves are a possible cause of pain, transcatheter arterial embolization (TAE) has been reported as a novel adjunctive treatment with good outcomes. Purpose of this was to examine the short-term outcomes of TAE including 1-day follow-up results in patients with chronic shoulder pain using patient-reported outcome measures.

Study Design: Prospective study.

Methods: TAE was performed with a suspension of imipenem/cilastatin sodium in contrast agent. Subjects were assessed before, 1 day after, and 1 month after the procedure using the visual analogue scale (VAS, 0–10), shoulder pain and disability index (SPADI, 0–100), and Constant–Murley score (CMS, 0–100).

Results: A total of 10 patients were enrolled. All procedures were technically successful with the radial artery approach. Abnormal neovessels with angiographic blushes were identified in all cases, with a mean of 3.3 abnormal neovessels per patient (range, 2–4) and a total of 41 arteries embolized, averaging 4.1 vessels per patient (range, 3–5). Baseline VAS, SPADI, and CMS were 3.5, 50.0, and 47.4, respectively. The 1-day follow-up (VAS, 2.0; SPADI, 26.3; CMS, 68.1; p ≤ 0.001 compared to baseline) and 1-month follow-up (VAS, 1.7; SPADI, 24.3; CMS, 72.8; p ≤ 0.002 compared to baseline) demonstrated significant improvements. The 1-day and 1-month follow-up results were not significantly different.

Conclusions: Substantial pain relief and functional scales improvement were observed both immediately and 1 month after TAE in chronic intractable shoulder pain. TAE may be an effective alternative treatment for patients with shoulder pain who do not respond to conservative or surgical treatment.

Trial Registration: Korean Registry of Clinical Trials: KCT0004720

Abstract Image

查看原文本刊更多论文

经导管动脉栓塞治疗慢性难治性肩痛的效果：一项前瞻性临床研究

目的：基于新血管和神经是疼痛的可能原因的观点，经导管动脉栓塞（TAE）作为一种新的辅助治疗方法已被报道，效果良好。本研究的目的是检查TAE的短期结果，包括使用患者报告的结果测量方法对慢性肩痛患者进行1天的随访结果。研究设计：前瞻性研究。方法：采用亚胺培南/西司他汀钠混悬液造影剂行TAE。采用视觉模拟量表（VAS, 0-10）、肩痛和残疾指数（SPADI, 0-100）和Constant-Murley评分（CMS, 0-100）对受试者进行术前、术后1天和术后1个月的评估。结果：共纳入10例患者。所有桡动脉入路手术在技术上都是成功的。所有病例均发现异常新血管伴血管造影红，平均每位患者3.3个异常新血管（范围2-4），共有41个动脉栓塞，平均每位患者4.1个血管（范围3-5）。基线VAS、SPADI和CMS分别为3.5、50.0和47.4。1天随访(VAS, 2.0；SPADI 26.3;CMS, 68.1;与基线相比p≤0.001)和1个月随访(VAS, 1.7；SPADI 24.3;CMS, 72.8;P≤0.002（与基线相比）显示显著改善。1天和1个月随访结果无显著差异。结论：慢性难治性肩痛患者在TAE治疗后立即和1个月均可观察到明显的疼痛缓解和功能量表改善。对于保守或手术治疗无效的肩痛患者，TAE可能是一种有效的替代治疗方法。试验注册：韩国临床试验注册中心：KCT0004720

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Clinical Practice 医学-医学：内科

CiteScore

5.30

自引率

0.00%

发文量

274

审稿时长

3-8 weeks

期刊介绍： IJCP is a general medical journal. IJCP gives special priority to work that has international appeal. IJCP publishes: Editorials. IJCP Editorials are commissioned. [Peer reviewed at the editor''s discretion] Perspectives. Most IJCP Perspectives are commissioned. Example. [Peer reviewed at the editor''s discretion] Study design and interpretation. Example. [Always peer reviewed] Original data from clinical investigations. In particular: Primary research papers from RCTs, observational studies, epidemiological studies; pre-specified sub-analyses; pooled analyses. [Always peer reviewed] Meta-analyses. [Always peer reviewed] Systematic reviews. From October 2009, special priority will be given to systematic reviews. [Always peer reviewed] Non-systematic/narrative reviews. From October 2009, reviews that are not systematic will be considered only if they include a discrete Methods section that must explicitly describe the authors'' approach. Special priority will, however, be given to systematic reviews. [Always peer reviewed] ''How to…'' papers. Example. [Always peer reviewed] Consensus statements. [Always peer reviewed] Short reports. [Always peer reviewed] Letters. [Peer reviewed at the editor''s discretion] International scope IJCP publishes work from investigators globally. Around 30% of IJCP articles list an author from the UK. Around 30% of IJCP articles list an author from the USA or Canada. Around 45% of IJCP articles list an author from a European country that is not the UK. Around 15% of articles published in IJCP list an author from a country in the Asia-Pacific region.