Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium (Adv. Biology 4/2025)

Abstract

Influenza A

Mucus serves as a physical and adhesive barrier to infectious agents in the lung. The article number 2400329 by Gregg A. Duncan and co-workers demonstrates how the penetration of flu virus through the mucus barrier is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans.