Impact of consultation liaison services on postoperative psychotropic drug use

IF 3.5 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research Pub Date : 2025-04-10 DOI:10.1016/j.jpsychores.2025.112123

Riki Kitaoka , Nobutaka Ayani , Takahiro Uramatsu , Eriko Yamazoe , Tomoya Okazaki , Kyohei Ogawa , Takato Yokoi , Keisuke Takeda , Koju Nakai , Nozomu Oya , Takeshi Nakamura , Go Horiguchi , Jin Narumoto

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引用次数: 0

Abstract

Objective

In clinical practice, most cases of postoperative delirium are treated by an attending surgeon who is not a specialist in delirium treatment. We investigated the postoperative use of psychotropic drugs with and without psychiatric consultation liaison service (CLS).

Method

Patients who received specific psychotropic drugs postoperatively under general anesthesia were included. The participants were divided into two groups, with and without CLS intervention. The type and dosage of psychotropic drugs used, presence of delirium, and adverse drug events (ADEs) caused by psychotropic drugs administered postoperatively were investigated.

Results

Of the 509 patients who were newly prescribed the psychotropic drugs postoperatively, 67 patients (13 %) received CLS intervention. In the non-CLS group, 65 % (43/66) of patients who received antipsychotics after surgery did not have delirium, which was significantly higher than in the CLS group (65 % vs 22 %, p < 0.01). Haloperidol was the most commonly used antipsychotic postoperatively, and the median daily dose was significantly higher in the non-CLS group (0.22 mg/day vs 0.38 mg/day, p = 0.04).

Conclusion

CLS interventions may contribute to a reduction in unnecessary administration of antipsychotic drugs and dosages.

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会诊联络服务对术后精神药物使用的影响

目的在临床实践中，大多数术后谵妄病例由非谵妄治疗专家的主治医生治疗。我们调查了有无精神科咨询联络服务（CLS）的术后精神药物使用情况。方法选取全麻下接受特定精神药物治疗的患者。参与者被分为两组，有和没有CLS干预。调查患者使用精神药物的种类和剂量、谵妄的存在以及术后使用精神药物引起的不良事件（ADEs）。结果509例术后新开精神药物的患者中，67例（13%）接受了CLS干预。在非CLS组中，术后接受抗精神病药物治疗的患者中65%（43/66）没有出现谵妄，明显高于CLS组(65% vs 22%, p <；0.01)。氟哌啶醇是术后最常用的抗精神病药物，非cls组的中位日剂量明显更高（0.22 mg/天vs 0.38 mg/天，p = 0.04）。结论cls干预可能有助于减少不必要的抗精神病药物的使用和剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Psychosomatic Research 医学-精神病学

CiteScore

7.40

自引率

6.40%

发文量

314

审稿时长

6.2 weeks

期刊介绍： The Journal of Psychosomatic Research is a multidisciplinary research journal covering all aspects of the relationships between psychology and medicine. The scope is broad and ranges from basic human biological and psychological research to evaluations of treatment and services. Papers will normally be concerned with illness or patients rather than studies of healthy populations. Studies concerning special populations, such as the elderly and children and adolescents, are welcome. In addition to peer-reviewed original papers, the journal publishes editorials, reviews, and other papers related to the journal''s aims.