Dynalog-based dose verification in PRIMO Monte Carlo for IMRT and VMAT head and neck cancer

IF 2.8 3区 物理与天体物理 Q3 CHEMISTRY, PHYSICAL
Mochamad Robby Fairuzzihab Qodarul , Dea Ryangga , Andrian Dede Handika , Supriyanto Ardjo Pawiro , Akbar Azzi
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Abstract

Modern linear accelerator (linac) nowadays writes the treatment delivery log within its system. This log can be reconstructed into treatment plan format as an input for the independent dose calculation (IDC) to evaluate the planned dose distribution. PRIMO, one of the Monte Carlo simulation user codes, can perform IDC using both plan parameter and treatment log history. This study aims to verify the planned dose to reconstructed log dose distribution and evaluates the use of treatment Dynalog for IDC at PRIMO program. A total of 5 planning and Dynalog files for 7-field IMRT and 2-arc VMAT head and neck cancer cases were simulated in PRIMO and compared to treatment plan dose distribution. The evaluation metrics were gamma pass rate (GPR) and percentage of agreement (PA) for delineated structure, and root-mean-square error (RMS) of multi-leaf collimators (MLC). The GPR evaluation with criteria of 3 %/3 mm, 3 %/2 mm and 2 %/2 mm were within the tolerance level of 95 %. On the other hand, PA results showed less than 99 % for almost all structures. The average of IMRT RMS was 0.020 and VMAT was 0.022. These results were below the tolerance level of 3.5 mm of dynamic MLC. The dose verification method using GPRs and RMS was relevant because the evaluation results produced within the recommendations, stricter limits of GPR 2 %/2 mm 95 % and RMS < 1 mm could be applied. The PA could not be the sole evaluator but complement other parameters for verification.
基于动态模拟的 PRIMO 蒙特卡洛剂量验证,用于 IMRT 和 VMAT 头颈部癌症治疗
现代直线加速器(linac)现在在其系统内写入处理交付日志。该日志可以重构为治疗计划格式,作为独立剂量计算(IDC)的输入,以评估计划剂量分布。PRIMO是蒙特卡罗模拟用户代码之一,可以使用计划参数和处理日志历史执行IDC。本研究旨在验证计划剂量以重建对数剂量分布,并评估治疗Dynalog在PRIMO项目中用于IDC的使用情况。在PRIMO中模拟7场IMRT和2弧VMAT头颈癌病例的5个计划和动态文件,并与治疗计划剂量分布进行比较。评价指标为伽玛通过率(GPR)和描绘结构的一致性百分比(PA),以及多叶准直器(MLC)的均方根误差(RMS)。3 %/3 mm、3 %/2 mm和2 %/2 mm的GPR评价标准均在95%的公差范围内。另一方面,PA结果显示几乎所有结构都小于99%。IMRT平均RMS为0.020,VMAT平均RMS为0.022。这些结果低于3.5 mm动态MLC的耐受水平。使用GPR和RMS的剂量验证方法是相关的,因为评估结果符合建议,GPR 2% / 2mm≥95%和RMS <;可施1毫米。PA不能是唯一的评估者,而是补充其他参数进行验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Radiation Physics and Chemistry
Radiation Physics and Chemistry 化学-核科学技术
CiteScore
5.60
自引率
17.20%
发文量
574
审稿时长
12 weeks
期刊介绍: Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.
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