Sarcoidosis

Abstract

Sarcoidosis is a systemic inflammatory disease characterized by the formation of non-caseating granulomas that can affect any organ, with the lung being the most characteristic. Demonstrating non-necrotizing granulomas in a biopsy is essential in order to establish a diagnosis in practically all cases. Other additional tests, such as blood and urine tests, imaging and respiratory function tests, and bronchoalveolar lavage are useful in the diagnosis. The mainstay of treatment is corticosteroids, although immunosuppressive and biologic drugs may be useful.