Effect of Slope-Reducing Tibial Osteotomy With Primary Anterior Cruciate Ligament Reconstruction on Clinical and Radiological Results in Patients With a Steep Posterior Tibial Slope and Excessive Anterior Tibial Subluxation: Propensity Score Matching With a Minimum 2-Year Follow-up

Daofeng Wang, Menglinqian Di, Tong Zheng, Chengcheng Lv, Yang Liu, Guanyang Song, Hui Zhang
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Abstract

Background: A steep posterior tibial slope (PTS) and excessive anterior tibial subluxation of the lateral compartment (ASLC) have been considered to be associated with inferior graft outcomes in primary anterior cruciate ligament (ACL) reconstruction (ACLR). Case series studies have demonstrated that combined slope-reducing tibial osteotomy can greatly improve knee functional scores and stability in revision ACLR. However, there is currently no comparative study evaluating the clinical benefits of osteotomy procedures in primary ACLR. Purpose: To assess the feasibility of combined slope-reducing tibial osteotomy and primary ACLR in patients with a steep PTS and excessive ASLC and to explore the suitable threshold for osteotomy. Study Design: Case series; Level of evidence, 4. Methods: Between 2016 and 2022, of the 108 patients with ACL injuries who had a steep PTS (≥15°) and a follow-up ≥2 years, 30 patients with excessive ASLC (≥6 mm) underwent concomitant slope-reducing tibial osteotomy and ACLR (osteotomy group), and 78 patients underwent isolated ACLR (control group). Propensity score matching at a 1:2 ratio was used to match preoperative variables between the 2 groups. After matching preoperative variables, 25 and 48 patients underwent combined surgery and isolated ACLR, respectively. The primary outcome was ACL graft status (failure and laxity rates). The secondary outcomes were ASLC and anterior tibial subluxation of the medial compartment (ASMC), KT-1000 arthrometer side-to-side difference (SSD), pivot-shift grade, and second-look arthroscopic findings. Stratified analysis was performed with 1° PTS increments to explore the osteotomy threshold. Results: Both groups were comparable in terms of age, sex, side, body mass index, PTS, graft diameter, time from injury to surgery, ASLC, ASMC, KT-1000 arthrometer SSD, pivot-shift grade, and meniscal injuries (all P > .05). The mean PTS significantly decreased from 18.2° to 6.7° ( P < .001) in the osteotomy group. The 2-year rate of ACL graft laxity was 12.0% in the osteotomy group and 35.4% in the control group, with a statistically significant difference ( P = .033). There was no significant difference in the 2-year rate of ACL graft failure between the 2 groups (8.0% vs 12.5%, respectively; P = .559). The final follow-up data showed that improvements in ASLC (4.5 vs 6.4 mm, respectively; P = .012) and ASMC (2.8 vs 4.5 mm, respectively; P = .014) were more significant in the osteotomy group compared with the control group. On the second-look arthroscopic examination, the incidence of graft roof impingement in the control group was significantly higher than that in the osteotomy group (22.9% vs 4.0%, respectively; P = .039). No significant differences were observed between the 2 groups in terms of KT-1000 arthrometer SSD and high-grade pivot shift ( P > .05). Furthermore, stratified analysis revealed that the combined procedure significantly reduced the ACL graft failure rate and improved the KT-1000 arthrometer SSD in patients with a preoperative PTS ≥16°. Conclusion: Slope-reducing tibial osteotomy combined with primary ACLR significantly decreased the amount of anterior tibial subluxation, the incidence of graft roof impingement, and the graft laxity rate for patients with a steep PTS (≥15°) and excessive ASLC (≥6 mm). Furthermore, in patients with a PTS ≥16°, the combined procedure improved anterior knee stability and reduced the graft failure rate. Therefore, a PTS ≥16° plus ASLC ≥6 mm may be considered an appropriate indication for combining slope-reducing tibial osteotomy with primary ACLR.
胫骨减坡截骨合并初级前交叉韧带重建对胫骨后坡陡峭和胫骨前半脱位患者临床和影像学结果的影响:倾向评分与至少2年随访相匹配
背景:在原发性前交叉韧带(ACL)重建(ACLR)中,胫骨后坡(PTS)和胫骨前外侧室(ASLC)过度半脱位被认为与移植物预后较差有关。病例系列研究表明,联合胫骨减坡截骨术可以大大提高ACLR翻修时膝关节功能评分和稳定性。然而,目前还没有比较研究评估截骨术治疗原发性ACLR的临床益处。目的:评价陡PTS伴ASLC过多患者行胫骨减坡截骨联合原发性ACLR的可行性,探讨合适的截骨阈值。研究设计:病例系列;证据等级,4级。方法:2016 - 2022年,在108例具有陡峭PTS(≥15°)的ACL损伤患者中,随访≥2年,30例过度ASLC(≥6 mm)患者同时行胫骨减坡截骨和ACLR(截骨组),78例患者行孤立ACLR(对照组)。采用1:2比例的倾向评分匹配来匹配两组之间的术前变量。在匹配术前变量后,分别有25例和48例患者接受了联合手术和孤立ACLR。主要结果是前交叉韧带移植状态(失败和松弛率)。次要结果是ASLC和胫骨前内侧室半脱位(ASMC), KT-1000关节计侧侧差(SSD),枢轴移位等级和二次关节镜检查结果。以1°PTS增量进行分层分析以探索截骨阈值。结果:两组患者在年龄、性别、侧面、体重指数、PTS、移植物直径、损伤至手术时间、ASLC、ASMC、KT-1000关节计SSD、枢轴移位等级和半月板损伤(均P >;. 05)。平均PTS从18.2°显著下降到6.7°(P <;.001)。截骨组2年ACL移植物松弛率为12.0%,对照组为35.4%,差异有统计学意义(P = 0.033)。两组间2年ACL移植失败率无显著差异(分别为8.0%和12.5%;P = .559)。最终随访数据显示ASLC改善(分别为4.5 vs 6.4 mm;P = 0.012)和ASMC(分别为2.8 vs 4.5 mm;P = 0.014),截骨组与对照组比较,差异有统计学意义。二次关节镜检查时,对照组植骨顶撞击发生率明显高于截骨组(22.9% vs 4.0%;P = .039)。两组在KT-1000关节计SSD和高级别枢轴移位(P >;. 05)。此外,分层分析显示,在术前PTS≥16°的患者中,联合手术显著降低了ACL移植失败率,并改善了KT-1000关节计SSD。结论:对于陡峭PTS(≥15°)和过度ASLC(≥6 mm)的患者,胫骨减坡截骨联合原发性ACLR可显著降低胫骨前半脱位的数量、移植物顶撞击的发生率和移植物松弛率。此外,在PTS≥16°的患者中,联合手术改善了膝关节前稳定性并降低了移植物失败率。因此,PTS≥16°加上ASLC≥6mm可被认为是胫骨减坡截骨联合原发性ACLR的合适适应症。
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