Cucurbitane Triterpenoids from the Whole Herb of Chrysosplenium carnosum

Abstract

Chrysosplenium carnosum, an original plant used in traditional Tibetan medicine known as “Yajima”, was subjected to phytochemical study. This led to the isolation of a new hexanor-cucurbitane triterpenoid, namely chrycarnin A (1), along with three previously known structurally related analogs (2–4). Their structures were determined by spectroscopic methods, including 1D and 2D NMR, UV, IR, ECD, and HR-ESI-MS, and comparison of the spectroscopic data with those reported in the literature.