Alzheimer disease seen through the lens of sex and gender

IF 28.2 1区 医学 Q1 CLINICAL NEUROLOGY
Laura Castro-Aldrete, Melanie Einsiedler, Julie Novakova Martinkova, Herman Depypere, Ting Fang Alvin Ang, Michelle M. Mielke, Shireen Sindi, Harris A. Eyre, Rhoda Au, Anne Marie Schumacher Dimech, Anna Dé, Cassandra Szoeke, Maria Carmela Tartaglia, Antonella Santuccione Chadha
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引用次数: 0

Abstract

Alzheimer disease (AD) is a life-limiting neurodegenerative disorder that disproportionately affects women. Indeed, sex and gender are emerging as crucial modifiers of diagnostic and therapeutic pathways in AD. This Review provides an overview of the interactions of sex and gender with important developments in AD and offers insights into priorities for future research to facilitate the development and implementation of personalized approaches in the shifting paradigm of AD care. In particular, this Review focuses on the influence of sex and gender on important advances in the treatment and diagnosis of AD, including disease-modifying therapies, fluid-based biomarkers, cognitive assessment tools and multidomain lifestyle interventional studies.

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从性和性别角度看阿尔茨海默病
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来源期刊
Nature Reviews Neurology
Nature Reviews Neurology 医学-临床神经学
CiteScore
29.90
自引率
0.80%
发文量
138
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.
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