Two telomere-to-telomere pig genome assemblies and pan-genome analyses provide insights into genomic structural landscape and genetic adaptations

IF 23.7 Q1 MICROBIOLOGY
iMeta Pub Date : 2025-04-03 DOI:10.1002/imt2.70013
Wencheng Zong, Li Chen, Dongjie Zhang, Yuebo Zhang, Jinbu Wang, Xinhua Hou, Jie Chai, Yalong An, Ming Tian, Xinmiao He, Chengyi Song, Jun He, Xin Liu, Ligang Wang, Enrico D'Alessandro, Lixian Wang, Yulong Yin, Mingzhou Li, Di Liu, Jinyong Wang, Longchao Zhang
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引用次数: 0

Abstract

This study presented two high-precision telomere-to-telomere genome assemblies for Min and Rongchang pigs, including a detailed exploration of the telomeric and centromeric regions. By integrating pan-genome and multi-omics analyses, structural variations linked to genetic adaptation were identified, providing a valuable resource for advancing pig breeding and genetic improvement.

Abstract Image

两个端粒到端粒的猪基因组组装和泛基因组分析提供了基因组结构景观和遗传适应的见解
本研究介绍了闽猪和荣昌猪的两个高精度端粒到端粒基因组组装,包括对端粒和着丝粒区域的详细探索。通过整合泛基因组和多组学分析,确定了与遗传适应相关的结构变异,为推进猪的育种和遗传改良提供了宝贵的资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
10.80
自引率
0.00%
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