Clinical impact of surgical energy device (Caiman®) IN elderly patients with Endometrial Cancer (protocol ID: Cineca)

IF 3.5 2区医学 Q2 ONCOLOGY

Ejso Pub Date : 2025-03-25 DOI:10.1016/j.ejso.2025.109982

Federica Perelli , Martina Arcieri , Stefano Restaino , Alberto Mattei , Salvatore Gueli Alletti , Valerio Gallotta , Giovanni Scambia , Chiara Innocenzi , Barbara Costantini , Giuseppe Vizzielli

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引用次数: 0

Abstract

Study objective

To investigate the clinical performance of the Caiman® energy device in class A radical laparoscopic hysterectomy (RLH) according to Querleu-Morrow classification, combined with bilateral salpingo-oophorectomy (BSO) and pelvic lymph node assessment in elderly patients with early-stage endometrial cancer (EC), specifically focusing on hemostatic effectiveness and safety.

Design

Single-institution, prospective observational study.

Setting

Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Patients

Forty-three women over 65 years with FIGO stage IA or IB endometrioid EC were enrolled from September 2021 to August 2023.

Interventions

Use of Caiman® energy device in RLH combined with BSO and pelvic lymph node assessment in elderly patients.

Measurements

The primary endpoint was operative time, with secondary endpoints including perioperative outcomes and postoperative complications.

Main results

Results demonstrated a median surgical time of 135 min, with no significant intraoperative complications attributed to the Caiman® device. Postoperative complications were minimal, with no severe complications (Grade 4 or 5) and a median hospital stay of two days.

Conclusion

The study highlights the advantages of the Caiman® in enhancing surgical efficiency while minimizing risks for elderly patients, suggesting its potential for improving resource allocation and patient outcomes in oncologic surgery. The findings of this study suggest the feasibility of using the Caiman® device for surgical procedures in elderly patients with early-stage endometrial cancer. Future prospective randomized trials are needed to establish its efficacy compared to traditional surgical methods.

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手术能量装置（Caiman®）对老年子宫内膜癌患者的临床影响（方案ID: Cineca）

研究目的探讨Caiman®能量装置在基于Querleu-Morrow分类的A类根治性腹腔镜子宫切除术（RLH）中的临床表现，并结合双侧输卵管卵巢切除术（BSO）和盆腔淋巴结评估对老年早期子宫内膜癌（EC）患者止血的有效性和安全性。设计：单机构、前瞻性观察研究。背景：意大利，罗马，意大利，吉梅利大学，妇科肿瘤科。患者：从2021年9月至2023年8月，43名65岁以上FIGO期IA或IB期子宫内膜样EC的女性入组。Caiman®能量装置对老年RLH患者联合BSO及盆腔淋巴结评估的干预效果。主要终点是手术时间，次要终点包括围手术期结局和术后并发症。主要结果显示，中位手术时间为135分钟，没有明显的术中并发症归因于凯门®装置。术后并发症极少，无严重并发症（4级或5级），平均住院时间为2天。结论本研究强调了Caiman®在提高老年患者手术效率和降低风险方面的优势，提示其在肿瘤手术中改善资源分配和患者预后的潜力。本研究结果表明，在老年早期子宫内膜癌患者的外科手术中使用Caiman®装置是可行的。需要未来的前瞻性随机试验来确定其与传统手术方法相比的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ejso 医学-外科

CiteScore

6.40

自引率

2.60%

发文量

1148

审稿时长

41 days

期刊介绍： JSO - European Journal of Surgical Oncology ("the Journal of Cancer Surgery") is the Official Journal of the European Society of Surgical Oncology and BASO ~ the Association for Cancer Surgery. The EJSO aims to advance surgical oncology research and practice through the publication of original research articles, review articles, editorials, debates and correspondence.