Se and N doped hierarchical porous carbon nanozyme-mediated colorimetric sensing array for antioxidants discrimination

IF 8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Sensors and Actuators B: Chemical Pub Date : 2025-04-13 DOI:10.1016/j.snb.2025.137785

Lijuan Yan , Xiangkun Jia , Ruimin Li , Peipei Zong , Chengjie Chen , Dongbo Yan , Xiaotong Li , Congxiao Wang , Yanling Zhai , Lei Jiao

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引用次数: 0

Abstract

Although nanozymes-mediated turn-off colorimetric sensing of antioxidants has been extensively investigated, the investigation of specific inhibition between nanozymes and antioxidants is still a challenge. Herein, selenium and nitrogen co-doped carbon nanozymes (Se-NC) with hierarchical porous structure were successfully prepared and demonstrated enhanced peroxidase (POD)-like activity. Besides, the reversible inhibitory effect between antioxidants and Se-NC nanozymes is confirmed based on the Lineweaver-Burk plots. According to the specific inhibitory effect of antioxidants toward on the POD-like activity of prepared nanozymes, a colorimetric sensor array is established for the identification of antioxidants. The research designs a nanozyme with enhanced POD-like activity and provides insights into inhibition mechanisms between nanozymes and the corresponding inhibitor.

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硒和氮掺杂分层多孔碳纳米酶介导的抗氧化剂识别比色传感阵列

尽管纳米酶介导的抗氧化剂熄灭比色传感技术已得到广泛研究，但纳米酶与抗氧化剂之间的特异性抑制研究仍是一项挑战。本文成功制备了具有分层多孔结构的硒氮共掺杂碳纳米分子（Se-NC），并显示出增强的过氧化物酶（POD）样活性。此外，根据 Lineweaver-Burk 图，还证实了抗氧化剂与 Se-NC 纳米酶之间的可逆抑制作用。根据抗氧化剂对所制备纳米酶 POD 样活性的特异性抑制作用，建立了一种用于识别抗氧化剂的比色传感器阵列。该研究设计了一种具有增强 POD 样活性的纳米酶，并深入探讨了纳米酶与相应抑制剂之间的抑制机制。

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来源期刊

Sensors and Actuators B: Chemical 工程技术-电化学

CiteScore

14.60

自引率

11.90%

发文量

1776

审稿时长

3.2 months

期刊介绍： Sensors & Actuators, B: Chemical is an international journal focused on the research and development of chemical transducers. It covers chemical sensors and biosensors, chemical actuators, and analytical microsystems. The journal is interdisciplinary, aiming to publish original works showcasing substantial advancements beyond the current state of the art in these fields, with practical applicability to solving meaningful analytical problems. Review articles are accepted by invitation from an Editor of the journal.