Biotechnological potential of Monascus: Biological aspects, metabolites of interest, and opportunities for new products

IF 6.9 1区生物学 Q1 MICROBIOLOGY

Microbiological research Pub Date : 2025-04-10 DOI:10.1016/j.micres.2025.128177

Gabriel Leda Arruda , Willian S.M. Reis , Maria Teresa F.R. Raymundo , Vinícius P. Shibukawa , Mónica M. Cruz-Santos , Nayeli Ortiz Silos , Carina A. Prado , Paulo R.F. Marcelino , Silvio S. da Silva , Júlio C. Santos

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Abstract

The need to develop more sustainable products and processes qualifies microbial platforms for obtaining products as a highlighted interesting solution. In this context, filamentous fungi that produce biopigments have been emphasized, especially in the development of research, products and industrial applications. Among the different species, the genus Monascus stands out, either because of its popular use in traditional communities or even because of its versatile growth capacity. Indeed, it is able to metabolize different substrates, including agro-industrial wastes and by-products, as well as allowing different cultivation approaches, such as solid-state and submerged fermentation, for the production of biopigments. Its best-known products include biopigments (yellow, orange and red) and diverse secondary metabolites which have proven biological properties and have great potential in food, pharmaceutical and cosmetic formulations. This review presents the biotechnological, biochemical, and innovation potential of fungi from the genus Monascus, encompassing their historical importance, recent studies on cultivation and production of biopigments, beside the potential of this emerging platform for producing microbial biopigments.

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红曲霉的生物技术潜力：生物学方面，感兴趣的代谢物，以及新产品的机会

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来源期刊

Microbiological research 生物-微生物学

CiteScore

10.90

自引率

6.00%

发文量

249

审稿时长

29 days

期刊介绍： Microbiological Research is devoted to publishing reports on prokaryotic and eukaryotic microorganisms such as yeasts, fungi, bacteria, archaea, and protozoa. Research on interactions between pathogenic microorganisms and their environment or hosts are also covered.