Neutrophil extracellular traps associated RNA impedes CD4+ Treg differentiation by TLR7-IRF7 axis in ankylosing spondylitis

IF 11.4 1区医学 Q1 RHEUMATOLOGY

Arthritis & Rheumatology Pub Date : 2025-04-10 DOI:10.1002/art.43166

Zhikun Li, Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Jinteng Li, Wenhui Yu, Guiwen Ye, Guan Zheng, Zipeng Xiao, Yanfeng Wu, Huiyong Shen, Zhongyu Xie

引用次数: 0

Abstract

To investigate the role of neutrophil extracellular traps (NETs) in the pathogenesis of inflammatory disorders in ankylosing spondylitis (AS).

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中性粒细胞胞外捕获物相关 RNA 通过 TLR7-IRF7 轴阻碍强直性脊柱炎中 CD4+ Treg 的分化

研究中性粒细胞胞外捕获物（NET）在强直性脊柱炎（AS）炎症性疾病发病机制中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arthritis & Rheumatology RHEUMATOLOGY-

CiteScore

20.90

自引率

3.00%

发文量

371

期刊介绍： Arthritis & Rheumatology is the official journal of the American College of Rheumatology and focuses on the natural history, pathophysiology, treatment, and outcome of rheumatic diseases. It is a peer-reviewed publication that aims to provide the highest quality basic and clinical research in this field. The journal covers a wide range of investigative areas and also includes review articles, editorials, and educational material for researchers and clinicians. Being recognized as a leading research journal in rheumatology, Arthritis & Rheumatology serves the global community of rheumatology investigators and clinicians.