Fe–Cu nanoparticle-modified calcium phosphate coatings: enhanced antimicrobial and biocompatibility properties

IF 0.4 4区 物理与天体物理 Q4 PHYSICS, MULTIDISCIPLINARY
V. V. Chebodaeva, O. V. Bakina, Yu. P. Sharkeev
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引用次数: 0

Abstract

Calcium phosphate (CaP) coatings modified with Fe–Cu nanoparticles have been manufactured using the micro-arc oxidation (MAO) method. The primary focus was on the morphology, elemental composition, phase composition, and surface charge properties as well as the antimicrobial activity and cytotoxicity of the coatings. It is demonstrated that the addition of the Fe–Cu nanoparticles enhances the antimicrobial properties of the coatings by reducing the number of viable Staphylococcus aureus bacteria and increases the biocompatibility of the coatings. This makes the coatings promising for use in medical implants, providing the necessary composition and porosity along with the improved biological characteristics.

铁铜纳米粒子修饰磷酸钙涂层:增强抗菌和生物相容性
采用微弧氧化(MAO)法制备了Fe-Cu纳米颗粒改性磷酸钙(CaP)涂层。主要研究了涂层的形态、元素组成、相组成、表面电荷性质以及抗菌活性和细胞毒性。结果表明,Fe-Cu纳米粒子的加入通过减少金黄色葡萄球菌的活菌数量来提高涂层的抗菌性能,并提高涂层的生物相容性。这使得涂层有望用于医疗植入物,提供必要的成分和孔隙度以及改进的生物特性。
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来源期刊
Russian Physics Journal
Russian Physics Journal PHYSICS, MULTIDISCIPLINARY-
CiteScore
1.00
自引率
50.00%
发文量
208
审稿时长
3-6 weeks
期刊介绍: Russian Physics Journal covers the broad spectrum of specialized research in applied physics, with emphasis on work with practical applications in solid-state physics, optics, and magnetism. Particularly interesting results are reported in connection with: electroluminescence and crystal phospors; semiconductors; phase transformations in solids; superconductivity; properties of thin films; and magnetomechanical phenomena.
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