The effect of acupuncture on reducing postoperative complications in fracture patients: A retrospective analysis using the TriNetX database

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM

Bone Reports Pub Date : 2025-04-04 DOI:10.1016/j.bonr.2025.101842

Yi-Pin Chang , Hsin-Hua Chen , Jui-Ju Tseng , Chia-I Tsai

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引用次数: 0

Abstract

Background

Bone fracture is a common orthopedic condition that affects millions of people worldwide. The management frequently involves surgery, which requires hospitalization. Patients with fractures often have a risk of developing complications, including pain, inflammation, infection, delayed healing, thrombosis, and organ failure. Acupuncture is widely used for conditions such as pain, respiratory issues, urinary system disorders, and gastrointestinal discomfort.

Methods

In this retrospective study, we evaluated the effectiveness of acupuncture in reducing postoperative complications in fracture patients. Using the TriNetX platform, we identified individuals hospitalized for their first fracture surgery and performed 1: 1 propensity score matching. Patients who received three or more acupuncture treatments within one week (n = 433) were compared to those who received none (n = 433), with matching based on age, sex, race, BMI, comorbidities, and medications (standardized mean differences). Postoperative complications within 180 days were analyzed using risk percentages, risk ratios, odds ratios, Kaplan-Meier analysis with log-rank tests, and hazard ratios, all reported with 95 % confidence intervals and P-values.

Results

Fourteen patients in the acupuncture group experienced respiratory failure with a risk of 3.2 %, while 29 patients in the non-acupuncture group developed respiratory failure with a risk of 6.7 %. The risk ratio was 0.48 (95 % CI 0.26–0.90) and the OR was 0.47 (95 % CI 0.24–0.89). The Kaplan-Meier analysis found a significantly higher survival probability in the acupuncture group (log-rank test P = 0.01; HR 0.44, 95%CI 0.23–0.83).

Conclusions

Acupuncture appeared to have the potential to reduce postoperative complications in bone fracture patients. Further large-scale studies are needed to provide stronger evidence.

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针刺对减少骨折患者术后并发症的影响：使用TriNetX数据库的回顾性分析

骨骨折是一种常见的骨科疾病，影响着全世界数百万人。治疗通常包括手术，这需要住院治疗。骨折患者通常有发生并发症的风险，包括疼痛、炎症、感染、延迟愈合、血栓形成和器官衰竭。针灸被广泛用于治疗疼痛、呼吸系统疾病、泌尿系统疾病和胃肠道不适等疾病。方法回顾性研究针刺治疗骨折患者术后并发症的效果。使用TriNetX平台，我们确定了首次住院接受骨折手术的患者，并进行了1:1的倾向评分匹配。将一周内接受三次或三次以上针灸治疗的患者（n = 433）与未接受针灸治疗的患者（n = 433）进行比较，并根据年龄、性别、种族、BMI、合并症和药物进行匹配（标准化平均差异）。采用风险百分比、风险比、优势比、Kaplan-Meier log-rank检验分析和风险比分析180天内的术后并发症，所有报告的置信区间和p值均为95%。结果针刺组有14例患者发生呼吸衰竭，风险为3.2%；非针刺组有29例患者发生呼吸衰竭，风险为6.7%。风险比为0.48 (95% CI 0.26-0.90)， OR为0.47 （95% CI 0.24-0.89）。Kaplan-Meier分析发现，针刺组患者的生存率显著高于针刺组(log-rank检验P = 0.01；Hr 0.44, 95%ci 0.23-0.83)。结论针刺治疗有减少骨折患者术后并发症的潜力。需要进一步的大规模研究来提供更有力的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bone Reports Medicine-Orthopedics and Sports Medicine

CiteScore

4.30

自引率

4.00%

发文量

444

审稿时长

57 days

期刊介绍： Bone Reports is an interdisciplinary forum for the rapid publication of Original Research Articles and Case Reports across basic, translational and clinical aspects of bone and mineral metabolism. The journal publishes papers that are scientifically sound, with the peer review process focused principally on verifying sound methodologies, and correct data analysis and interpretation. We welcome studies either replicating or failing to replicate a previous study, and null findings. We fulfil a critical and current need to enhance research by publishing reproducibility studies and null findings.