{"title":"Balloon aortic valvuloplasty for congenital aortic valvar stenosis in 10 dogs","authors":"R.L. Winter , B.A. Scansen , K.L. Maneval , C.S. Ferrel , B.M. Potter , M.K. Ames , P.-T. Liao , S.W. Jung","doi":"10.1016/j.jvc.2025.03.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Aortic valvar stenosis (AS) is an uncommon congenital defect in the dog, but when present, it can cause severe clinical signs including collapse and congestive heart failure. In human patients, AS is a common congenital defect that has been managed with balloon aortic valvuloplasty (BAV). The objectives of this study were to describe the procedural details and retrospectively evaluate the outcomes of dogs with severe AS that underwent BAV.</div></div><div><h3>Animals</h3><div>Ten client-owned dogs diagnosed with severe AS.</div></div><div><h3>Materials and Methods</h3><div>Medical records and stored images from echocardiographic and angiographic examinations were reviewed from dogs that were diagnosed with severe AS and underwent BAV. The severity of velocity-derived maximal systolic pressure gradient across the aortic valve and aortic insufficiency was assessed from transthoracic echocardiographic images before and after BAV. Procedural details from the BAV procedures including intra-operative complications, type and size of the balloon catheter used, and use of rapid right ventricular pacing were recorded.</div></div><div><h3>Results</h3><div>The median (range) age and weight at the time of BAV were 12 months (6–120 months) and 18.2 kg (4.8–33.0 kg), respectively. Most dogs had high-pressure balloon dilation catheters used (n = 6/10) during BAV, and the balloon diameter-to-aortic annular ratio was 1.03 ± 0.05 for all dogs. The maximal systolic pressure gradient across the aortic valve decreased from 183.2 mmHg ± 74.6 before BAV to 97.4 mmHg ± 48.2 immediately after BAV (P<0.001). The severity of aortic insufficiency did not significantly worsen after BAV (P=0.25). The long-term impact of BAV on survival is unknown, and this could be considered a limitation of this study.</div></div><div><h3>Study Limitations</h3><div>This study describes the short-term effects of BAV for dogs with AS, and a lack of long-term follow-up may be considered a limitation.</div></div><div><h3>Conclusions</h3><div>Balloon aortic valvuloplasty for severe AS is tolerated in most dogs, and dogs with severe AS may benefit from transcatheter BAV.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"59 ","pages":"Pages 61-69"},"PeriodicalIF":1.5000,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Cardiology","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1760273425000268","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction/Objectives
Aortic valvar stenosis (AS) is an uncommon congenital defect in the dog, but when present, it can cause severe clinical signs including collapse and congestive heart failure. In human patients, AS is a common congenital defect that has been managed with balloon aortic valvuloplasty (BAV). The objectives of this study were to describe the procedural details and retrospectively evaluate the outcomes of dogs with severe AS that underwent BAV.
Animals
Ten client-owned dogs diagnosed with severe AS.
Materials and Methods
Medical records and stored images from echocardiographic and angiographic examinations were reviewed from dogs that were diagnosed with severe AS and underwent BAV. The severity of velocity-derived maximal systolic pressure gradient across the aortic valve and aortic insufficiency was assessed from transthoracic echocardiographic images before and after BAV. Procedural details from the BAV procedures including intra-operative complications, type and size of the balloon catheter used, and use of rapid right ventricular pacing were recorded.
Results
The median (range) age and weight at the time of BAV were 12 months (6–120 months) and 18.2 kg (4.8–33.0 kg), respectively. Most dogs had high-pressure balloon dilation catheters used (n = 6/10) during BAV, and the balloon diameter-to-aortic annular ratio was 1.03 ± 0.05 for all dogs. The maximal systolic pressure gradient across the aortic valve decreased from 183.2 mmHg ± 74.6 before BAV to 97.4 mmHg ± 48.2 immediately after BAV (P<0.001). The severity of aortic insufficiency did not significantly worsen after BAV (P=0.25). The long-term impact of BAV on survival is unknown, and this could be considered a limitation of this study.
Study Limitations
This study describes the short-term effects of BAV for dogs with AS, and a lack of long-term follow-up may be considered a limitation.
Conclusions
Balloon aortic valvuloplasty for severe AS is tolerated in most dogs, and dogs with severe AS may benefit from transcatheter BAV.
期刊介绍:
The mission of the Journal of Veterinary Cardiology is to publish peer-reviewed reports of the highest quality that promote greater understanding of cardiovascular disease, and enhance the health and well being of animals and humans. The Journal of Veterinary Cardiology publishes original contributions involving research and clinical practice that include prospective and retrospective studies, clinical trials, epidemiology, observational studies, and advances in applied and basic research.
The Journal invites submission of original manuscripts. Specific content areas of interest include heart failure, arrhythmias, congenital heart disease, cardiovascular medicine, surgery, hypertension, health outcomes research, diagnostic imaging, interventional techniques, genetics, molecular cardiology, and cardiovascular pathology, pharmacology, and toxicology.