Knockout of extended pelvic lymph node dissection during radical cystectomy

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2025-04-09 DOI:10.1038/s41585-025-01029-3

Kilian M. Gust, Shahrokh F. Shariat

引用次数: 0

Abstract

Results from the SWOG S1011 and LEA trials show that extended pelvic lymph node dissection during radical cystectomy for muscle-invasive bladder cancer offers no survival benefit. Novel perioperative systemic therapies could lead to true survival improvement for patients with muscle-invasive bladder cancer undergoing radical surgery and have the potential to implement bladder-preserving strategies.

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根治性膀胱切除术中扩大盆腔淋巴结清扫的剔除

SWOG S1011和LEA试验的结果表明，在肌肉浸润性膀胱癌根治性膀胱切除术中，扩大盆腔淋巴结清扫并没有带来生存益处。新的围手术期全身疗法可能会导致肌肉侵袭性膀胱癌患者接受根治性手术的真正生存改善，并有可能实施膀胱保留策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.