{"title":"Accessible technology for diploid high-order 3D human genome analysis","authors":"","doi":"10.1038/s41594-025-01519-3","DOIUrl":null,"url":null,"abstract":"We developed a method that improves the detection of haplotype-assigned chromatin interactions in humans by over tenfold, using far less data than traditional methods. This advance enabled an almost complete diploid 3D genome map, making high-order phased chromatin interaction studies more accessible to researchers.","PeriodicalId":18822,"journal":{"name":"Nature structural & molecular biology","volume":"118 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature structural & molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41594-025-01519-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We developed a method that improves the detection of haplotype-assigned chromatin interactions in humans by over tenfold, using far less data than traditional methods. This advance enabled an almost complete diploid 3D genome map, making high-order phased chromatin interaction studies more accessible to researchers.
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