Acute Corneal Epithelial Detachment During Lid Speculum Placement Prior to Intravitreal Injection in a Diabetic Patient: A Case Report.

IF 1.4 Q3 OPHTHALMOLOGY

Clinical Optometry Pub Date : 2025-04-04 eCollection Date: 2025-01-01 DOI:10.2147/OPTO.S508943

Qian-Qian Guo, Luxin Zhao, Wei Zhu

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Abstract

Introduction: Diabetic macular edema (DME) is a vision-threatening complication of diabetic retinopathy. Intravitreal anti-VEGF injections offer effective treatment, but they carry a risk of corneal epithelial detachment, particularly in patients who have recently undergone cataract surgery.

Case presentation: A 63-year-old male developed bilateral DME following cataract surgery with intraocular lens implantation. His best-corrected visual acuity (BCVA) was 0.15 in the right eye and 0.5 in the left eye. The patient underwent bilateral intravitreal injections of the anti-VEGF agent conbercept. During preparation for the injection in the left eye, corneal epithelial bleb formation was observed. The patient received corneal patching therapy, with complete epithelial healing observed by day 10 post-injection. This case underscores the need for vigilant corneal monitoring during and after intravitreal injections in diabetic patients with prior cataract surgery.

Conclusion: Close observation of corneal epithelial healing is crucial in diabetic patients receiving intravitreal injections, especially those with a recent history of cataract surgery. Careful pre-injection assessment and vigilant post-injection management are essential to mitigate this potential complication.

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来源期刊

Clinical Optometry OPHTHALMOLOGY-

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

16 weeks

期刊介绍： Clinical Optometry is an international, peer-reviewed, open access journal focusing on clinical optometry. All aspects of patient care are addressed within the journal as well as the practice of optometry including economic and business analyses. Basic and clinical research papers are published that cover all aspects of optics, refraction and its application to the theory and practice of optometry. Specific topics covered in the journal include: Theoretical and applied optics, Delivery of patient care in optometry practice, Refraction and correction of errors, Screening and preventative aspects of eye disease, Extended clinical roles for optometrists including shared care and provision of medications, Teaching and training optometrists, International aspects of optometry, Business practice, Patient adherence, quality of life, satisfaction, Health economic evaluations.