Evidences for gestures associated with pruritus in very young infants: a pilot study.

IF 3.8 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-04-08 DOI:10.1038/s41598-025-93412-8

Adrien Boyard, Camille Cosnard, David Simon, Camille Le Pors, Claire Abasq-Thomas, Marine Grandgeorge, Laurent Misery, Séverine Henry, Jean-Michel Roué

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引用次数: 0

Abstract

The anatomical and functional basis for pruritus is present from birth. However, pruritus in this population is largely underestimated. The aim of this study was to analyze behaviors potentially associated with pruritus in infants under 6 months suffering from atopic dermatitis (AD). Infants under 6 months of age were enrolled in two arms: a healthy group and a group with moderate or severe AD. Infants were videotaped for at least 5 min and videos were analyzed by ethologists using the scan-sampling method. Thirty-four infants aged 2.5-5.5 months were included, 9 healthy infants and 25 infants with AD. Hand movements were more frequent in the AD group than in the healthy infants (p < 0.01). Video analysis revealed the presence of self-contact with grasping movements, which could be identified as immature scratching behavior. The statistical distribution of this behavior was greater in the AD group (p 0.03). Correlation analyses showed that this scratching behavior was associated with SCORAD (p 0.04), but not with age. This is the first study to highlight behaviors that can be identified in infants with pruritus before they develop the motor capacity to scratch.

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幼儿瘙痒症与手势相关的证据：一项初步研究。

瘙痒症的解剖学和功能基础从出生就存在。然而，瘙痒症在这一人群中被大大低估了。本研究的目的是分析患有特应性皮炎（AD）的6个月以下婴儿与瘙痒的潜在相关行为。6个月以下的婴儿被分为两组：健康组和中度或重度AD组。对婴儿进行至少5分钟的录像，并由行为学家使用扫描取样法对录像进行分析。纳入34例2.5-5.5月龄婴儿，9例健康婴儿和25例AD婴儿。AD组的手部运动比健康婴儿更频繁(p

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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