Tianhao Huang, Zeyu Liang, Ke Wang, Xiangjun Miao, Lei Zheng
{"title":"Novel insights into athlete physical recovery concerning lactate metabolism, lactate clearance and fatigue monitoring: A comprehensive review.","authors":"Tianhao Huang, Zeyu Liang, Ke Wang, Xiangjun Miao, Lei Zheng","doi":"10.3389/fphys.2025.1459717","DOIUrl":null,"url":null,"abstract":"<p><p>Lactate accumulation will appear in athlete skeletal muscle after intense exercise. If the high lactate level maintains, athletes will sustain fatigue and athletic capacity decline due to internal environment and normal metabolism disruption. In order to enhance athlete physical recovery and exercise performance in high-intensity sport events, it is of great significance to explore the scientific intervention procedures based on quicker lactate clearance in skeletal muscle and blood after exercise. This article collects classic and novel literature in terms of lactate metabolism, lactate clearance and fatigue monitoring during exercise by searching PubMed database and then summarizes comprehensive insights into athlete physical recovery with corresponding figures and charts. We introduce the generation and transformation process of lactate, lactate clearance pathways and the fatigue monitoring methods for athletes in detail. The lactate clearance pathways involve biochemical pathways (oxygen inhalation, amino acids supplement, targeting free radical, alkaline reserve, targeting vasomotion, ribose supplement), physical activities (exercise-mediated activities, non-exercise activities) and training methods (interval training, altitude training) to accelerate lactate metabolism. The biochemical factors for monitoring athletic fatigue level involve blood, urine, sweat, saliva and exhaled gas. We hope this review can offer some significant and scientific assistance for athlete recovering after exercise and improving sport achievements based on quicker lactate clearance.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"16 ","pages":"1459717"},"PeriodicalIF":3.2000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975961/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fphys.2025.1459717","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Lactate accumulation will appear in athlete skeletal muscle after intense exercise. If the high lactate level maintains, athletes will sustain fatigue and athletic capacity decline due to internal environment and normal metabolism disruption. In order to enhance athlete physical recovery and exercise performance in high-intensity sport events, it is of great significance to explore the scientific intervention procedures based on quicker lactate clearance in skeletal muscle and blood after exercise. This article collects classic and novel literature in terms of lactate metabolism, lactate clearance and fatigue monitoring during exercise by searching PubMed database and then summarizes comprehensive insights into athlete physical recovery with corresponding figures and charts. We introduce the generation and transformation process of lactate, lactate clearance pathways and the fatigue monitoring methods for athletes in detail. The lactate clearance pathways involve biochemical pathways (oxygen inhalation, amino acids supplement, targeting free radical, alkaline reserve, targeting vasomotion, ribose supplement), physical activities (exercise-mediated activities, non-exercise activities) and training methods (interval training, altitude training) to accelerate lactate metabolism. The biochemical factors for monitoring athletic fatigue level involve blood, urine, sweat, saliva and exhaled gas. We hope this review can offer some significant and scientific assistance for athlete recovering after exercise and improving sport achievements based on quicker lactate clearance.
期刊介绍:
Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.