Ischemic preconditioning: exploring local ergogenic mechanisms in non-fatiguing voluntary contractions.

IF 3.2 3区医学 Q2 PHYSIOLOGY

Frontiers in Physiology Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI:10.3389/fphys.2025.1542394

Ruben Allois, Raffaele Pertusio, Pasquale Pagliaro, Silvestro Roatta

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引用次数: 0

Abstract

Background: IPC has been suggested to boost skeletal muscle performance, though its effectiveness remains controversial. This study evaluates whether IPC influences local hemodynamic responses and surface electromyographic (sEMG) activity during non-fatiguing voluntary sustained and intermittent contractions.

Methods: Ten male participants were subjected to IPC (3 cycles, 5-min ON/5-min OFF right arm ischemia, cuff pressure: 250 mmHg) and SHAM (same protocol at 20 mmHg) in two different sessions. Near-infrared spectroscopy was used to monitor tissue oxygenation (TOI) and deoxy-hemoglobin (HHb) in extensor and flexor forearm muscles. sEMG was also recorded. Measurements were taken during sustained (20-s duration) and intermittent (5 s ON/5 s OFF) isometric contractions at 20, 30, and 40% of the maximal voluntary contraction. These non-fatiguing exercise tasks were performed before and 30 min after the IPC/SHAM intervention.

Results: sEMG exhibited a significant increase post vs. pre-treatment in both IPC and SHAM in extensors. A significant decrease in TOI at rest was noted pre vs. post-treatment for both IPC and SHAM (p < 0.01). In general, no main effect of treatment was observed, except for HHb changes during contraction in extensor muscles, associated with no effect of time and no time-treatment interaction. All variables exhibited a main effect of force level (p < 0.05), with no interaction with treatment or time.

Conclusion: IPC had no effect on hemodynamic and electromyographic variables during sustained and intermittent handgrip. These results do not support IPC-related ergogenic effects at the muscle level, aligning with previous findings on electrically stimulated contractions.

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缺血预处理：探索非疲劳自发性收缩的局部经氧机制。

背景：IPC已被认为可以提高骨骼肌的性能，尽管其有效性仍存在争议。本研究评估IPC是否影响局部血流动力学反应和表面肌电图（sEMG）活动在非疲劳自愿持续和间歇性收缩。方法：10名男性受试者在两个不同的疗程中接受IPC（3个周期，5分钟ON/5分钟OFF右臂缺血，袖带压：250 mmHg）和SHAM（相同方案，20 mmHg）。采用近红外光谱法监测前臂伸、屈肌组织氧合（TOI）和脱氧血红蛋白（hbb）。同时记录表面肌电信号。测量在持续（20秒持续时间）和间歇（5秒开/5秒关）等长收缩时，在最大自主收缩的20%、30%和40%进行。这些非疲劳运动任务分别在IPC/SHAM干预前和干预后30分钟进行。结果：伸肌的IPC和SHAM在治疗后与治疗前相比，表面肌电信号明显增加。IPC和SHAM治疗前与治疗后相比，静止时TOI显著降低（p < 0.01）。一般来说，除了在伸肌收缩期间hb发生变化外，没有观察到治疗的主要效果，这与时间和时间-治疗相互作用无关。所有变量均表现为力水平的主要影响（p < 0.05），与治疗和时间无交互作用。结论：IPC对持续握力和间歇握力的血流动力学和肌电图参数无影响。这些结果不支持在肌肉水平上与ipc相关的人体产生效应，与先前关于电刺激收缩的研究结果一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Physiology PHYSIOLOGY-

CiteScore

6.50

自引率

5.00%

发文量

2608

审稿时长

14 weeks

期刊介绍： Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.