Effects of exercise training on left ventricular systolic and diastolic function after myocardial infarction: systematic review and meta-analysis.

IF 2.8 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Frontiers in Cardiovascular Medicine Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI:10.3389/fcvm.2025.1526326

XiaoMing Zhang, Yao Mi, Mingwang Ding, Xin Gao

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引用次数: 0

Abstract

Objectives: Exercise training is a rehabilitative approach to improve cardiac function in patients with myocardial infarction. However, evidence on the effectiveness of exercise training in these patients remains limited. In this meta-analysis, we aim to evaluate the extent to which exercise training improves cardiac function in patients with myocardial infarction.

Methods: We conducted a systematic search of the PubMed, Embase, Cochrane Library, and Web of Science databases to compare cardiac function in myocardial infarction patients who received exercise training combined with standard pharmacological therapy. The cardiac function indicators evaluated included: LVEF, E, E/A, LVIDd, LVIDs, NT-proBNP, E' septal, GLS, and LVMI.

Results: The final analysis included 12 studies with a total of 922 patients. Compared with the standard treatment group, exercise training significantly improved LVEF (MD = 3.99, 95% CI: 1.30-6.68) and E (MD = 3.86, 95% CI: 1.33-6.39) in myocardial infarction patients, while showing no significant improvement in the remaining indicators.

Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024571194, PROSPERO (CRD42024571194).

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来源期刊

Frontiers in Cardiovascular Medicine Medicine-Cardiology and Cardiovascular Medicine

CiteScore

3.80

自引率

11.10%

发文量

3529

审稿时长

14 weeks

期刊介绍： Frontiers? Which frontiers? Where exactly are the frontiers of cardiovascular medicine? And who should be defining these frontiers? At Frontiers in Cardiovascular Medicine we believe it is worth being curious to foresee and explore beyond the current frontiers. In other words, we would like, through the articles published by our community journal Frontiers in Cardiovascular Medicine, to anticipate the future of cardiovascular medicine, and thus better prevent cardiovascular disorders and improve therapeutic options and outcomes of our patients.