Effects of exercise in older adults with osteosarcopenic adiposity: a systematic review and meta-analysis of randomized controlled trials.

IF 2.2 3区医学 Q2 ORTHOPEDICS

BMC Musculoskeletal Disorders Pub Date : 2025-04-08 DOI:10.1186/s12891-025-08581-4

Lei Chen, Wenlu Zhou, Ju Li, Taotao Xu, Zhenyu Shi

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引用次数: 0

Abstract

Aim: To evaluate the effects of exercise training on patients with osteosarcopenic adiposity (OSA).

Methods: A comprehensive search was conducted in PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases for randomized controlled trials (RCTs) on exercise treatment for OSA patients. The search included both Chinese and English literature up to April 2024. Reference lists and grey literature were also reviewed. Two researchers independently screened the literature, extracted data, and assessed the quality of included studies. Meta-analysis was performed using RevMan 5.4 software.

Results: A total of 7 studies were included in this meta-analysis. Exercise interventions significantly improved bone mineral density (BMD) (MD = 0.0195, 95% CI: 0 to 0.02, P = 0.03), body fat (BF) (MD = -4.0, 95% CI: -5.46 to -2.54, P < 0.01), and hand grip strength (HGS) (MD = 3.13, 95% CI: 0.72 to 5.54, P = 0.01) in patients with OSA. However, no significant differences were observed in skeletal muscle mass index (SMI) (MD = 0.12, 95% CI: -0.26 to 0.50, P = 0.55), gait speed (GS) (SMD = 0.75, 95% CI: -1.26 to 2.76, P = 0.47), or C-reactive protein (CRP) (MD = -0.23, 95% CI: -0.90 to 0.44, P = 0.50).

Conclusion: Exercise interventions can effectively improve clinical symptoms and signs in OSA patients to varying degrees, highlighting the importance of exercise in the management of OSA.

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运动对老年骨质减少性肥胖的影响：随机对照试验的系统回顾和荟萃分析。

目的：探讨运动训练对骨质减少性肥胖（OSA）患者的影响。方法：综合检索PubMed、Embase、Cochrane Library、Web of Science、CNKI、万方、VIP等数据库，检索运动治疗OSA患者的随机对照试验（rct）。检索包括截至2024年4月的中文和英文文献。并对参考文献和灰色文献进行了综述。两位研究者独立筛选文献，提取数据，并评估纳入研究的质量。采用RevMan 5.4软件进行meta分析。结果：本meta分析共纳入7项研究。运动干预可显著改善骨密度（BMD）（MD = 0.0195, 95% CI: 0 ~ 0.02, P = 0.03）、体脂（BF）（MD = -4.0, 95% CI: -5.46 ~ -2.54， P）。结论：运动干预可不同程度地有效改善OSA患者的临床症状和体征，凸显运动在OSA管理中的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Musculoskeletal Disorders 医学-风湿病学

CiteScore

3.80

自引率

8.70%

发文量

1017

审稿时长

3-6 weeks

期刊介绍： BMC Musculoskeletal Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of musculoskeletal disorders, as well as related molecular genetics, pathophysiology, and epidemiology. The scope of the Journal covers research into rheumatic diseases where the primary focus relates specifically to a component(s) of the musculoskeletal system.