Characterization of chemical and bioreactivity properties of photooxidation reaction products from secondary organic aerosols (SOA) under high OH exposure condition

IF 4.2 2区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Atmospheric Environment Pub Date : 2025-04-04 DOI:10.1016/j.atmosenv.2025.121212

Ka Hei Lui , Xinye Zhu , Yik-Sze Lau , Tianhang Zhang , Gehui Wang , Hsiao-Chi Chuang , Kin Fai Ho

{"title":"Characterization of chemical and bioreactivity properties of photooxidation reaction products from secondary organic aerosols (SOA) under high OH exposure condition","authors":"Ka Hei Lui , Xinye Zhu , Yik-Sze Lau , Tianhang Zhang , Gehui Wang , Hsiao-Chi Chuang , Kin Fai Ho","doi":"10.1016/j.atmosenv.2025.121212","DOIUrl":null,"url":null,"abstract":"<div><div>The chemical and bioreactivity properties of photooxidation products emitted during high radical exposure conditions were characterized. The purpose was to simultaneously investigate the influences of the toxicity of photooxidation products from common anthropogenic and biogenic precursors (toluene, m-xylene and isoprene). The major ring-opening compounds were identified as pyruvic acid (C3H4O3), glyceric acid (C3H6O4), succinic acid (C4H6O4), malic acid (C4H6O5), tartaric acid (C4H6O6), 2,3-dihydroxy-glutaric acid (C5H8O6), glycolic acid (C2H4O3) and oxalic acid (C2H2O4) originated from the toluene and xylene-derived secondary organic aerosol (SOA) products in the analysis. The average LDH level from isoprene-derived SOA (0.77 μg/ml) was higher than the control (0.75 μg/ml) and the DCFH level from isoprene-derived SOA (228.73 RFU) was also higher than the control (215.18 RFU). In addition, the average LDH level from toluene-derived SOA (0.86 μg/ml) was higher than the isoprene (0.77 μg/ml). The IL-6 level from toluene-derived SOA (182.82 pg/ml) was higher than the xylene-derived SOA (173.00 pg/ml). These suggested enhanced cytotoxicity and cell membrane damage under toluene-derived SOA exposure. The isoprene-derived SOA induced higher DCFH levels of (228.73 RFU), implying the potential effects of particulate matter from SOA on the oxidative potential and rising cellular oxidant burden. The overall results suggest that the oxidation products can potentially cause various cytotoxic effects. This finding warrants further investigation into the toxicity profiles of SOA and regulation of SOA pollution.</div></div>","PeriodicalId":250,"journal":{"name":"Atmospheric Environment","volume":"352 ","pages":"Article 121212"},"PeriodicalIF":4.2000,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Atmospheric Environment","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1352231025001876","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

The chemical and bioreactivity properties of photooxidation products emitted during high radical exposure conditions were characterized. The purpose was to simultaneously investigate the influences of the toxicity of photooxidation products from common anthropogenic and biogenic precursors (toluene, m-xylene and isoprene). The major ring-opening compounds were identified as pyruvic acid (C₃H₄O₃), glyceric acid (C₃H₆O₄), succinic acid (C₄H₆O₄), malic acid (C₄H₆O₅), tartaric acid (C₄H₆O₆), 2,3-dihydroxy-glutaric acid (C₅H₈O₆), glycolic acid (C₂H₄O₃) and oxalic acid (C₂H₂O₄) originated from the toluene and xylene-derived secondary organic aerosol (SOA) products in the analysis. The average LDH level from isoprene-derived SOA (0.77 μg/ml) was higher than the control (0.75 μg/ml) and the DCFH level from isoprene-derived SOA (228.73 RFU) was also higher than the control (215.18 RFU). In addition, the average LDH level from toluene-derived SOA (0.86 μg/ml) was higher than the isoprene (0.77 μg/ml). The IL-6 level from toluene-derived SOA (182.82 pg/ml) was higher than the xylene-derived SOA (173.00 pg/ml). These suggested enhanced cytotoxicity and cell membrane damage under toluene-derived SOA exposure. The isoprene-derived SOA induced higher DCFH levels of (228.73 RFU), implying the potential effects of particulate matter from SOA on the oxidative potential and rising cellular oxidant burden. The overall results suggest that the oxidation products can potentially cause various cytotoxic effects. This finding warrants further investigation into the toxicity profiles of SOA and regulation of SOA pollution.

Abstract Image

查看原文本刊更多论文

高OH暴露条件下二次有机气溶胶（SOA）光氧化反应产物的化学和生物活性表征

研究了高自由基暴露条件下光氧化产物的化学性质和生物活性。目的是同时研究常见的人为和生物前体（甲苯、间二甲苯和异戊二烯）光氧化产物的毒性影响。主要开环化合物为丙酮酸（C3H4O3）、甘油酸（C3H6O4）、琥珀酸（C4H6O4）、苹果酸（C4H6O5）、酒石酸（C4H6O6）、2,3-二羟基戊二酸（C5H8O6）、乙醇酸（C2H4O3）和草酸（C2H2O4），来源于甲苯和二甲苯衍生的二次有机气溶胶（SOA）产物。异戊二烯衍生SOA的平均LDH水平（0.77 μg/ml）高于对照组（0.75 μg/ml）， DCFH水平（228.73 RFU）也高于对照组（215.18 RFU）。此外，甲苯衍生SOA的平均LDH水平（0.86 μg/ml）高于异戊二烯（0.77 μg/ml）。甲苯衍生SOA的IL-6水平（182.82 pg/ml）高于二甲苯衍生SOA （173.00 pg/ml）。这些结果表明，甲苯衍生的SOA暴露会增强细胞毒性和细胞膜损伤。异戊二烯衍生的SOA诱导更高的DCFH水平（228.73 RFU），这意味着SOA中的颗粒物对氧化电位和细胞氧化负荷的潜在影响。总体结果表明，氧化产物可能会引起各种细胞毒性作用。这一发现值得进一步研究SOA的毒性概况和SOA污染的监管。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Atmospheric Environment 环境科学-环境科学

CiteScore

9.40

自引率

8.00%

发文量

458

审稿时长

53 days

期刊介绍： Atmospheric Environment has an open access mirror journal Atmospheric Environment: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Atmospheric Environment is the international journal for scientists in different disciplines related to atmospheric composition and its impacts. The journal publishes scientific articles with atmospheric relevance of emissions and depositions of gaseous and particulate compounds, chemical processes and physical effects in the atmosphere, as well as impacts of the changing atmospheric composition on human health, air quality, climate change, and ecosystems.