Evaluating antimicrobial activity: Biogenic vs. Chemically functionalized zinc oxide nanoparticles

IF 2.7 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Letters Pub Date : 2025-04-08 DOI:10.1016/j.matlet.2025.138548

Sanhita Mandal , Chinmay Hazra , Neha Joshi , Ramkrishna Sen , Siddhartha Das , Karabi Das

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Abstract

This study introduces an unique approach to synthesize zinc oxide NPs using biogenic surfactants (rhamnolipid and surfactin) and compares their antimicrobial efficacy to sodium dodecyl sulphate functionalized ZnO. The surfactin tagged ZnO demonstrated 42.28% more bacterial inhibition and rhamnolipid showed 132% more inhibition against Gram-positive M. luteus (Ml) (ATCC 4698) than SDS functionalized ZnO while surfactin tagged ZnO demonstrated 9.5% and rhamnolipid tagged ZnO exhibited 35.6% more bacterial inhibition against Gram-negative E. coli (DH5 alpha) (CP026085) bacteria than SDS functionalized ZnO. The fluorescence microscopy revealed a synergistic effect of ZnO and biosurfactant in killing bacterial cells by ROS generation, and membrane disruption and destabilization. This green synthesis approach offers a sustainable alternative to toxic surfactants, contributing to solutions against antimicrobial-resistant bacteria.

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来源期刊

Materials Letters 工程技术-材料科学：综合

CiteScore

5.60

自引率

3.30%

发文量

1948

审稿时长

50 days

期刊介绍： Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials. Contributions include, but are not limited to, a variety of topics such as: • Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors • Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart • Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction • Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots. • Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing. • Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic • Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive