Gastrointestinal stromal tumor surgery in pediatrics.

Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Pub Date : 2025-04-07 DOI:10.54847/cp.2025.02.17

S D Israel, A Del Cañizo, S Monje, M Sáenz, J Bueno, J Ordóñez, L Pérez Egido, M A García Casillas, J A Cerdá, I Bada Bosch, M Fanjul, D Peláez, J C de Agustín

{"title":"Gastrointestinal stromal tumor surgery in pediatrics.","authors":"S D Israel, A Del Cañizo, S Monje, M Sáenz, J Bueno, J Ordóñez, L Pérez Egido, M A García Casillas, J A Cerdá, I Bada Bosch, M Fanjul, D Peláez, J C de Agustín","doi":"10.54847/cp.2025.02.17","DOIUrl":null,"url":null,"abstract":"Introduction: Gastrointestinal stromal tumors (GIST) are infrequent in pediatric patients. The management of metastatic and irresectable tumors is usually non-surgical, with tyrosine-kinase inhibitors being the treatment of choice.Clinical case: We present the case of a 14-year-old female patient with a metastatic and irresectable GIST treated with sunitinib that required surgery as a result of severe hemoperitoneum episodes with anemia and hemodynamic instability. A cytoreductive surgery with R2 resection margins was carried out. After a 10-year follow-up period, the patient remains under oncological treatment.Discussion: The treatment of metastatic and irresectable GIST consists of tyrosine-kinase inhibitors. Evidence regarding the role of surgery remains limited, which means extreme caution should be exerted when indicating surgical treatment. However, surgery is still a useful tool within the array of therapeutic options.","PeriodicalId":94306,"journal":{"name":"Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica","volume":"38 2","pages":"74-76"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54847/cp.2025.02.17","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: Gastrointestinal stromal tumors (GIST) are infrequent in pediatric patients. The management of metastatic and irresectable tumors is usually non-surgical, with tyrosine-kinase inhibitors being the treatment of choice.

Clinical case: We present the case of a 14-year-old female patient with a metastatic and irresectable GIST treated with sunitinib that required surgery as a result of severe hemoperitoneum episodes with anemia and hemodynamic instability. A cytoreductive surgery with R2 resection margins was carried out. After a 10-year follow-up period, the patient remains under oncological treatment.

Discussion: The treatment of metastatic and irresectable GIST consists of tyrosine-kinase inhibitors. Evidence regarding the role of surgery remains limited, which means extreme caution should be exerted when indicating surgical treatment. However, surgery is still a useful tool within the array of therapeutic options.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica

自引率

0.00%

发文量