Relative Grip Strength and Muscle-Strengthening Activity: Separate and Combined Associations with Type 2 Diabetes Mellitus.

IF 4.7 Q1 ENDOCRINOLOGY & METABOLISM

Journal of Obesity & Metabolic Syndrome Pub Date : 2025-04-08 DOI:10.7570/jomes24029

Yunmin Han, Yeon Soo Kim

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引用次数: 0

Abstract

Background: Grip strength and muscle-strengthening activity (MSA) have been independently associated with type 2 diabetes mellitus (T2DM). However, analyses that consider grip strength in conjunction with MSA, while factoring in age and sex as well, are limited. Therefore, we aimed to investigate the association of relative grip strength (RGS) and MSA, separately and in combination, with T2DM, considering differences in age and sex.

Methods: A total of 27,702 participants aged 19 years and older were included from 2014 to 2021 from the Korea National Health and Nutrition Examination Survey. The association between RGS, MSA, and T2DM was assessed using logistic regression analysis. Odds ratios (OR) and 95% confidence intervals (CI) were calculated for the independent and joint associations of RGS and MSA on T2DM prevalence.

Results: Highest (Q4) RGS levels were independently associated with lower odds of T2DM (OR, 0.39; 95% CI, 0.32 to 0.46; P for trend <0.001). Similarly, engaging in MSA 2 o 3 days per week was associated with lower odds of T2DM (OR, 0.80; 95% CI, 0.66 to 0.96), although the trend was not statistically significant (P for trend=0.775). In the joint analysis, participants with normal RGS and engaging in MSA ≥2 days per week had the lowest odds of T2DM (OR, 0.60; 95% CI, 0.51 to 0.70).

Conclusion: Higher RGS and engaging in MSA 2 to 3 days per week are independently associated with lower likelihood of T2DM. The combined association of normal RGS and MSA 2 days or more per week shows the greatest benefit for T2DM prevention.

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相对握力和肌肉强化活动：与2型糖尿病的单独和联合关联。

背景：握力和肌肉强化活动（MSA）与2型糖尿病（T2DM）独立相关。然而，在考虑年龄和性别因素的同时，将握力与MSA结合起来的分析是有限的。因此，考虑到年龄和性别的差异，我们的目的是研究相对握力（RGS）和MSA单独或联合与T2DM的关系。方法：从2014年到2021年，共纳入27,702名年龄在19岁及以上的参与者，这些参与者来自韩国国家健康与营养检查调查。采用logistic回归分析评估RGS、MSA和T2DM之间的关系。计算RGS和MSA与T2DM患病率的独立和联合关联的优势比（OR）和95%置信区间（CI）。结果：最高（Q4） RGS水平与较低的T2DM几率独立相关(OR, 0.39；95% CI, 0.32 ~ 0.46；P代表趋势P代表趋势=0.775)。在联合分析中，RGS正常且每周MSA≥2天的参与者患T2DM的几率最低(OR, 0.60；95% CI, 0.51 ~ 0.70)。结论：较高的RGS和每周2 - 3天的MSA与较低的T2DM可能性独立相关。每周2天或以上的正常RGS和MSA联合显示对T2DM预防的最大益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obesity & Metabolic Syndrome ENDOCRINOLOGY & METABOLISM-

CiteScore

8.30

自引率

9.60%

发文量

审稿时长

19 weeks

期刊介绍： The journal was launched in 1992 and diverse studies on obesity have been published under the title of Journal of Korean Society for the Study of Obesity until 2004. Since 2017, volume 26, the title is now the Journal of Obesity & Metabolic Syndrome (pISSN 2508-6235, eISSN 2508-7576). The journal is published quarterly on March 30th, June 30th, September 30th and December 30th. The official title of the journal is now "Journal of Obesity & Metabolic Syndrome" and the abbreviated title is "J Obes Metab Syndr". Index words from medical subject headings (MeSH) list of Index Medicus are included in each article to facilitate article search. Some or all of the articles of this journal are included in the index of PubMed, PubMed Central, Scopus, Embase, DOAJ, Ebsco, KCI, KoreaMed, KoMCI, Science Central, Crossref Metadata Search, Google Scholar, and Emerging Sources Citation Index (ESCI).