Cancer-Related Masculine Threat in Young Adult Testicular Cancer Survivors: Associations With Biobehavioral Symptoms.

IF 3.3 2区医学 Q2 ONCOLOGY

Psycho‐Oncology Pub Date : 2025-04-01 DOI:10.1002/pon.70124

Michael A Hoyt, Zixia Wang, Christian J Nelson

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引用次数: 0

Abstract

Objective: Cancer and cancer treatment have been experienced by some men as a threat to masculinity. Cancer-related masculine threat (CMT) reflects perceptions that cancer and cancer-related change are inconsistent with one's ideal masculine gender role. This secondary analysis examines associations of CMT with symptoms of sleep disturbance, anxiety, and depression, as well as levels of pro-inflammatory biomarkers in young adult men after testicular cancer.

Methods: Forty-four young adult men (M age = 28 years; SD = 4.1) who had undergone chemotherapy for testicular cancer within the prior 2 years completed questionnaires and provided blood samples for immune assessments. Patient-reported measures assessed CMT, depressive symptoms, anxiety, and sleep quality.

Results: CMT was significantly associated with poorer sleep quality (B = 0.50, p < 0.01), and more symptoms of depression (B = 0.47, p < 0.01) and anxiety (B = 0.54, p < 0.01). CMT was also related to higher circulating levels of IL-6 (B = 0.47, p < 0.05) and CRP (B = 0.33, p < 0.05), but not significantly associated with sTNFαRII.

Conclusions: This study provides preliminary evidence for the associations of CMT and biobehavioral symptoms after treatment for testicular cancer. The identification of modifiable processes underpinning such symptoms is crucial to the design of behavioral interventions to reduce and manage persistent symptoms.

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年轻成年睾丸癌幸存者的癌症相关男性威胁：与生物行为症状的关联

目的：癌症和癌症治疗对一些男性来说是对男性气概的威胁。癌症相关的男性威胁（CMT）反映了人们认为癌症和癌症相关的变化与理想的男性性别角色不一致。这项二级分析研究了CMT与睾丸癌后年轻成年男性睡眠障碍、焦虑和抑郁症状以及促炎生物标志物水平的关系。方法：44名年轻成年男性(M年龄= 28岁；SD = 4.1)前2年内接受过睾丸癌化疗的患者填写问卷并提供血液样本进行免疫评估。患者报告的测量评估了CMT、抑郁症状、焦虑和睡眠质量。结果：CMT与较差的睡眠质量显著相关（B = 0.50, p）。结论：本研究为睾丸癌治疗后CMT与生物行为症状的关联提供了初步证据。识别支持这些症状的可修改过程对于设计行为干预措施以减少和管理持续症状至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psycho‐Oncology 医学-心理学

CiteScore

6.30

自引率

8.30%

发文量

220

审稿时长

3-8 weeks

期刊介绍： Psycho-Oncology is concerned with the psychological, social, behavioral, and ethical aspects of cancer. This subspeciality addresses the two major psychological dimensions of cancer: the psychological responses of patients to cancer at all stages of the disease, and that of their families and caretakers; and the psychological, behavioral and social factors that may influence the disease process. Psycho-oncology is an area of multi-disciplinary interest and has boundaries with the major specialities in oncology: the clinical disciplines (surgery, medicine, pediatrics, radiotherapy), epidemiology, immunology, endocrinology, biology, pathology, bioethics, palliative care, rehabilitation medicine, clinical trials research and decision making, as well as psychiatry and psychology. This international journal is published twelve times a year and will consider contributions to research of clinical and theoretical interest. Topics covered are wide-ranging and relate to the psychosocial aspects of cancer and AIDS-related tumors, including: epidemiology, quality of life, palliative and supportive care, psychiatry, psychology, sociology, social work, nursing and educational issues. Special reviews are offered from time to time. There is a section reviewing recently published books. A society news section is available for the dissemination of information relating to meetings, conferences and other society-related topics. Summary proceedings of important national and international symposia falling within the aims of the journal are presented.