Changes in Corneal Densitometry Values of 50 Corneal Layers After Keratorefractive Lenticule Extraction (KLEx): A 6-Year Follow-Up.

IF 2.9 3区医学 Q1 OPHTHALMOLOGY

Journal of refractive surgery Pub Date : 2025-04-01 DOI:10.3928/1081597X-20250305-01

Li Li, Wenjing Gao, Fuqi Deng, Huazheng Cao, Xiaomei Zhen, Yan Wang

{"title":"Changes in Corneal Densitometry Values of 50 Corneal Layers After Keratorefractive Lenticule Extraction (KLEx): A 6-Year Follow-Up.","authors":"Li Li, Wenjing Gao, Fuqi Deng, Huazheng Cao, Xiaomei Zhen, Yan Wang","doi":"10.3928/1081597X-20250305-01","DOIUrl":null,"url":null,"abstract":"Purpose: To investigate the changes in the corneal densitometry (CD) values after keratorefractive lenticule extraction (KLEx) and their influencing factors.Methods: CD values of 50 layers of the right corneas of the participants, measured using a Pentacam (Oculus Optikgeräte GmbH) at different points after KLEx, were obtained from a database and analyzed. Repeated-measures analysis of variance was used to compare CDs between postoperative time, regions, and corneal depths.Results: Fifty-two participants were included. At 1 week after surgery, CDs of the corneal center, para-center, and non-incised periphery increased by 24.23%, 24.49%, and 11.42% at the superior and inferior 20 μm and 14.54%, 13.39%, and 7.82% at the superior and inferior 40 μm of the junctions of the corneal cap and stromal bed, respectively, from their preoperative values. No significant differences were observed in maximum CD values between the corneal center, para-center, and non-incised periphery groups between preoperative and 6-year postoperative measurements (P = .07, .81, and .96, respectively).Conclusions: There was an initial significant increase in CD, particularly near the junctions of the corneal cap and stromal bed. Maximum CDs returned to preoperative values after 6 years. [J Refract Surg. 2025;41(4):e365-e373.].","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 4","pages":"e365-e373"},"PeriodicalIF":2.9000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of refractive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/1081597X-20250305-01","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To investigate the changes in the corneal densitometry (CD) values after keratorefractive lenticule extraction (KLEx) and their influencing factors.

Methods: CD values of 50 layers of the right corneas of the participants, measured using a Pentacam (Oculus Optikgeräte GmbH) at different points after KLEx, were obtained from a database and analyzed. Repeated-measures analysis of variance was used to compare CDs between postoperative time, regions, and corneal depths.

Results: Fifty-two participants were included. At 1 week after surgery, CDs of the corneal center, para-center, and non-incised periphery increased by 24.23%, 24.49%, and 11.42% at the superior and inferior 20 μm and 14.54%, 13.39%, and 7.82% at the superior and inferior 40 μm of the junctions of the corneal cap and stromal bed, respectively, from their preoperative values. No significant differences were observed in maximum CD values between the corneal center, para-center, and non-incised periphery groups between preoperative and 6-year postoperative measurements (P = .07, .81, and .96, respectively).

Conclusions: There was an initial significant increase in CD, particularly near the junctions of the corneal cap and stromal bed. Maximum CDs returned to preoperative values after 6 years. [J Refract Surg. 2025;41(4):e365-e373.].

查看原文本刊更多论文

角膜屈光性晶状体摘除（KLEx）后50层角膜密度测量值的变化：6年随访。

目的：探讨角膜屈光性晶状体摘除（KLEx）术后角膜密度（CD）值的变化及其影响因素。方法：使用Pentacam （Oculus Optikgeräte GmbH）在KLEx术后不同时间点测量参与者50层右角膜的CD值，并从数据库中获取并分析。使用重复测量方差分析比较术后时间、区域和角膜深度之间的cd。结果：共纳入52例受试者。术后1周，角膜中心、旁中心和未切开周围的cd在20 μm上下处分别较术前增加24.23%、24.49%和11.42%，在角膜帽与基质床交界处的40 μm上下处分别增加14.54%、13.39%和7.82%。在术前和术后6年的测量中，角膜中心组、近中心组和未切割的周围组的最大CD值无显著差异（P分别为0.07、0.81和0.96）。结论：初始CD显著增加，尤其是角膜帽和间质床交界处附近。最大CDs在6年后恢复到术前值。[J].中国光学精密工程，2015;41(4):368 - 378。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

$Journal of refractive surgery$

Journal of refractive surgery 医学-外科

CiteScore

5.10

自引率

12.50%

发文量

160

审稿时长

4-8 weeks

期刊介绍： The Journal of Refractive Surgery, the official journal of the International Society of Refractive Surgery, a partner of the American Academy of Ophthalmology, has been a monthly peer-reviewed forum for original research, review, and evaluation of refractive and lens-based surgical procedures for more than 30 years. Practical, clinically valuable articles provide readers with the most up-to-date information regarding advances in the field of refractive surgery. Begin to explore the Journal and all of its great benefits such as: • Columns including “Translational Science,” “Surgical Techniques,” and “Biomechanics” • Supplemental videos and materials available for many articles • Access to current articles, as well as several years of archived content • Articles posted online just 2 months after acceptance.