{"title":"Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments.","authors":"Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu","doi":"10.3389/fphys.2025.1457197","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aims to enhance the efficiency and accuracy of thyroid nodule segmentation in ultrasound images, ultimately improving nodule detection and diagnosis. For clinical deployment on mobile and embedded devices, DeepLabV3+ strives to achieve a balance between a lightweight architecture and high segmentation accuracy.</p><p><strong>Methodology: </strong>A comprehensive dataset of ultrasound images was meticulously curated using a high-resolution ultrasound imaging device. Data acquisition adhered to standardized protocols to ensure high-quality imaging. Preprocessing steps, including noise reduction and contrast optimization, were applied to enhance image clarity. Expert radiologists provided ground truth labels through meticulous annotation. To improve segmentation performance, we integrated MobileNetV2 and Depthwise Separable Dilated Convolution into the Atrous Spatial Pyramid Pooling (ASPP) module, incorporating the Pyramid Pooling Module (PPM) and attention mechanisms. To mitigate classification imbalances, we employed Tversky loss functions in the ultrasound image classification process.</p><p><strong>Results: </strong>In semantic image segmentation, DeepLabV3+ achieved an impressive Intersection over Union (IoU) of 94.37%, while utilizing only 12.4 MB of parameters, including weights and biases. This remarkable accuracy demonstrates the effectiveness of our approach. A high IoU value in medical imaging analysis reflects the model's ability to accurately delineate object boundaries.</p><p><strong>Conclusion: </strong>DeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. The obtained segmentation results suggest promising directions for future research, especially in the early detection of thyroid nodules. Deploying this algorithm on mobile devices offers a practical solution for early diagnosis and is likely to improve patient outcomes.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"16 ","pages":"1457197"},"PeriodicalIF":3.2000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973906/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fphys.2025.1457197","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This study aims to enhance the efficiency and accuracy of thyroid nodule segmentation in ultrasound images, ultimately improving nodule detection and diagnosis. For clinical deployment on mobile and embedded devices, DeepLabV3+ strives to achieve a balance between a lightweight architecture and high segmentation accuracy.
Methodology: A comprehensive dataset of ultrasound images was meticulously curated using a high-resolution ultrasound imaging device. Data acquisition adhered to standardized protocols to ensure high-quality imaging. Preprocessing steps, including noise reduction and contrast optimization, were applied to enhance image clarity. Expert radiologists provided ground truth labels through meticulous annotation. To improve segmentation performance, we integrated MobileNetV2 and Depthwise Separable Dilated Convolution into the Atrous Spatial Pyramid Pooling (ASPP) module, incorporating the Pyramid Pooling Module (PPM) and attention mechanisms. To mitigate classification imbalances, we employed Tversky loss functions in the ultrasound image classification process.
Results: In semantic image segmentation, DeepLabV3+ achieved an impressive Intersection over Union (IoU) of 94.37%, while utilizing only 12.4 MB of parameters, including weights and biases. This remarkable accuracy demonstrates the effectiveness of our approach. A high IoU value in medical imaging analysis reflects the model's ability to accurately delineate object boundaries.
Conclusion: DeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. The obtained segmentation results suggest promising directions for future research, especially in the early detection of thyroid nodules. Deploying this algorithm on mobile devices offers a practical solution for early diagnosis and is likely to improve patient outcomes.
期刊介绍:
Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.