Evaluating the Early Operational Performance of the Endocrine Module in the Athlete Biological Passport.

IF 2.6 3区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Drug Testing and Analysis Pub Date : 2025-04-07 DOI:10.1002/dta.3892

Miguel de Figueiredo, Alexandre Marchand, Damien Rhumorbarbe, Richard Mann, Jonas Saugy, Neil Robinson, Louisa M Lobigs, Magnus Ericsson

引用次数: 0

Abstract

In collaboration with various Anti-Doping Organisations and the Paris WADA-accredited laboratory, the International Testing Agency spearheaded the implementation of the Endocrine Module ahead of the Olympic Games Paris 2024. This article presents a data-driven evaluation of its early integration within Athlete Biological Passport (ABP) programmes. The assessment of endocrine profile testing follows the complete ABP sample lifecycle, from collection to the submission of reports by the Athlete Passport Management Unit. The article identifies both challenges and opportunities by integrating testing, analytical and ABP perspectives and offers recommendations for the future development of the Endocrine Module. furthermore, it explores the Endocrine Module's synergy with the haematological and steroidal modules emphasising on key areas for the enhancement of ABP programmes as a whole.

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评价运动员生物护照中内分泌模块的早期操作性能。

国际检测机构与多个反兴奋剂组织和世界反兴奋剂机构认可的巴黎实验室合作，在2024年巴黎奥运会之前率先实施了内分泌模块。这篇文章提出了一个数据驱动的评估，其早期整合在运动员生物护照（ABP）计划。内分泌测试的评估遵循完整的ABP样本生命周期，从收集到运动员护照管理部门提交报告。本文通过整合测试、分析和ABP的观点，确定了挑战和机遇，并对内分泌模块的未来发展提出了建议。此外，它还探讨了内分泌模块与血液学和类固醇模块的协同作用，强调了整个增强ABP计划的关键领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL

CiteScore

5.90

自引率

24.10%

发文量

191

审稿时长

2.3 months

期刊介绍： As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.