Evaluating the Early Operational Performance of the Endocrine Module in the Athlete Biological Passport.

IF 2.6 3区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Drug Testing and Analysis Pub Date : 2025-04-07 DOI:10.1002/dta.3892

Miguel de Figueiredo, Alexandre Marchand, Damien Rhumorbarbe, Richard Mann, Jonas Saugy, Neil Robinson, Louisa M Lobigs, Magnus Ericsson

引用次数: 0

Abstract

In collaboration with various Anti-Doping Organisations and the Paris WADA-accredited laboratory, the International Testing Agency spearheaded the implementation of the Endocrine Module ahead of the Olympic Games Paris 2024. This article presents a data-driven evaluation of its early integration within Athlete Biological Passport (ABP) programmes. The assessment of endocrine profile testing follows the complete ABP sample lifecycle, from collection to the submission of reports by the Athlete Passport Management Unit. The article identifies both challenges and opportunities by integrating testing, analytical and ABP perspectives and offers recommendations for the future development of the Endocrine Module. furthermore, it explores the Endocrine Module's synergy with the haematological and steroidal modules emphasising on key areas for the enhancement of ABP programmes as a whole.

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来源期刊

Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL

CiteScore

5.90

自引率

24.10%

发文量

191

审稿时长

2.3 months

期刊介绍： As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.