Visibility evaluation of gastric epithelial neoplasm of fundic gland mucosa lineage using texture and color enhancement imaging

IF 1.4 Q4 GASTROENTEROLOGY & HEPATOLOGY

DEN open Pub Date : 2025-04-08 DOI:10.1002/deo2.70110

Hisanori Utsunomiya, Hiroya Ueyama, Tsutomu Takeda, Shunsuke Nakamura, Yasuko Uemura, Tomoyo Iwano, Momoko Yamamoto, Ryota Uchida, Daiki Abe, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Mariko Hojo, Shuko Nojiri, Takashi Yao, Akihito Nagahara

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引用次数: 0

Abstract

Objectives

Recently, the incidence of Helicobacter pylori-uninfected gastric cancers, such as gastric epithelial neoplasm of fundic-gland mucosa lineage (GEN-FGML), has increased with the widespread use of eradication therapy. Because the detection and endoscopic diagnosis of GEN-FGML are difficult, an effective observation method in screening endoscopy is required. We investigated whether texture and color enhancement imaging (TXI) improved the visibility of GEN-FGML compared with white light imaging (WLI).

Methods

In this single-center prospective clinical study, 50 GEN-FGML lesions (35 patients) treated at our hospital between October 2020 and June 2023 were analyzed. The endoscopic images of GEN-FGML obtained using WLI, TXI mode 1 (TXI-1), TXI mode 2 (TXI-2), and narrow-band imaging were compared by 10 endoscopists. We analyzed the visibility score and inter-rater reliability (intraclass correlation coefficient and conducted an objective evaluation based on L* a* b* color values and the color difference (ΔE*) in the CIE LAB color space system.

Results

Histologically, GEN-FGML was classified as gastric adenocarcinoma of fundic-gland type (n = 45) and gastric adenocarcinoma of fundic-gland mucosa type (n = 5). The total visibility score for all endoscopists was significantly higher for TXI than for WLI (p < 0.01); and for TXI-1 than for TXI-2 (p < 0.01). The intraclass correlation coefficients for TXI-1 and TXI-2 were “almost perfect” and “substantial,” respectively, for all endoscopists. ΔE* was significantly higher for TXI than for WLI (p < 0.01).

Conclusions

TXI improved the visibility of GEN-FGML for all endoscopists compared with WLI when evaluated subjectively and objectively.

Abstract Image

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利用纹理和彩色增强成像评价胃底腺粘膜系上皮肿瘤的可见性

近年来，随着根治疗法的广泛应用，未感染幽门螺杆菌的胃癌，如胃底腺粘膜系上皮肿瘤（GEN-FGML）的发病率有所增加。由于GEN-FGML的检测和内镜诊断困难，因此需要一种有效的内镜筛查观察方法。我们研究了纹理和颜色增强成像（TXI）与白光成像（WLI）相比是否能提高GEN-FGML的可见性。方法在这项单中心前瞻性临床研究中，对2020年10月至2023年6月在我院治疗的50例GEN-FGML病变（35例）进行分析。比较10名内镜医师使用WLI、TXI模式1 （TXI-1）、TXI模式2 （TXI-2）和窄带成像获得的GEN-FGML内镜图像。我们分析了可见性得分和等级间信度（类内相关系数），并基于CIE LAB色彩空间系统中的L* a* b*色彩值和色差（ΔE*）进行了客观评价。结果组织学上将GEN-FGML分为基底腺型胃腺癌（n = 45）和基底腺粘膜型胃腺癌（n = 5）。所有内镜医师对TXI的总可见性评分均显著高于WLI (p <；0.01);TXI-1比TXI-2 (p <；0.01)。对于所有内窥镜医师而言，TXI-1和TXI-2的类内相关系数分别为“几乎完美”和“实质性”。ΔE* TXI显著高于WLI (p <；0.01)。结论与WLI相比，TXI在主客观评估时提高了所有内窥镜医师GEN-FGML的可见性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

DEN open

CiteScore

1.30

自引率

0.00%

发文量