Structural and functional analysis of the eye according to the accommodation-age relationship

IF 1.5 4区心理学 Q4 NEUROSCIENCES

Vision Research Pub Date : 2025-04-09 DOI:10.1016/j.visres.2025.108596

María Arcas-Carbonell , Elvira Orduna-Hospital , Sara Oliete-Lorente , María Mechó-García , Guisela Fernández-Espinosa , Ana Sanchez-Cano

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Abstract

This study investigates how accommodative demand affects ocular function by examining variations in the anterior chamber depth (ACD), as well as the retinal and anterior surface curvatures of the crystalline lens across different age groups.

The study included 96 right eyes from healthy individuals aged 18 to 66 years. Accommodation was assessed using an aberrometer under demands up to 5 diopters (D). Images of the anterior segment and retina were recorded and analyzed with custom software to adjust these surfaces to conic curves, providing data on changes in ACD, anterior surface curvature of the crystalline lens, and retinal shape during accommodation.

The average age of participants was 35.42 ± 13.55 years. Accommodation matched the demand at low levels (up to 1D) but under-accommodated at higher demands. No significant differences were found in the anterior surface curvature of the crystalline lens with increased accommodation, though a weak trend was observed in younger individuals. ACD significantly decreased with accommodation due to the anterior displacement of the lens. Retinal curvature showed significant changes, including flattening, with increased accommodative demand. There were correlations between the anterior surface eccentricity of the crystalline lens and both ACD changes and retinal eccentricity.

In conclusion, accommodation effectively responds to demands up to 1D across all ages. Our findings suggest a tendency for retinal curvature to flatten to higher demands, requiring further validation. While the central curvature of the anterior surface of the crystalline lens does not change significantly, ACD decreases with accommodation, indicating how age and presbyopia influence accommodative capacity and structural changes in the eye.

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根据适应-年龄关系分析眼睛的结构和功能

本研究通过检查不同年龄组的前房深度（ACD）以及视网膜和晶状体前表面曲率的变化，探讨了适应性需求如何影响眼功能。该研究包括来自18至66岁的健康个体的96只右眼。在高达5屈光度(D)的要求下，使用像差仪评估调节。记录前段和视网膜的图像，并使用定制软件进行分析，将这些表面调整为圆锥曲线，提供调节期间ACD变化、晶状体前表面曲率和视网膜形状的数据。参与者平均年龄为35.42±13.55岁。住宿满足低水平（至1D）的需求，但较高需求的住宿不足。虽然在年轻人中观察到微弱的趋势，但在晶状体的前表面曲率随着调节的增加而没有发现显著的差异。由于晶状体前移位，ACD随调节而显著降低。随着调节需求的增加，视网膜曲率发生了显著变化，包括变平。晶状体前表面偏心率与ACD变化及视网膜偏心率均有相关性。总之，住宿有效地响应了所有年龄段的需求。我们的研究结果表明，视网膜曲率趋于平坦，以更高的要求，需要进一步验证。虽然晶状体前表面的中心曲率没有明显变化，但ACD随着调节而降低，这表明年龄和老花眼如何影响眼睛的调节能力和结构变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vision Research 医学-神经科学

CiteScore

3.70

自引率

16.70%

发文量

111

审稿时长

66 days

期刊介绍： Vision Research is a journal devoted to the functional aspects of human, vertebrate and invertebrate vision and publishes experimental and observational studies, reviews, and theoretical and computational analyses. Vision Research also publishes clinical studies relevant to normal visual function and basic research relevant to visual dysfunction or its clinical investigation. Functional aspects of vision is interpreted broadly, ranging from molecular and cellular function to perception and behavior. Detailed descriptions are encouraged but enough introductory background should be included for non-specialists. Theoretical and computational papers should give a sense of order to the facts or point to new verifiable observations. Papers dealing with questions in the history of vision science should stress the development of ideas in the field.